When analysing and presenting results ofrandomised clinical trials, trialists rarely report if or how underlying statisticalassumptions were validated. To avoid data-driven biased trial results, it should ...
This paper focuses on the problem of testing the null hypothesis that the variance functions of two populations are equal versus one-sided alternatives under a general nonparametric heteroscedastic regression ...
We analyze the utility of multiscale supervised classification algorithms for object detection and extraction from laser scanning or photogrammetric point clouds. Only the geometric information (the point ...
Inulin-rich foods exert a prebiotic effect, as this polysaccharide is able to enhance beneficial colon microbiota populations, giving rise to the in situ production of short-chain fatty acids (SCFAs) such ...
The evaluation of mediastinal lymph nodes is critical for the correct staging of patients with lung cancer (LC). Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally ...
BACKGROUND & AIMS: Guidelines recommend individuals with familial colorectal cancer (FCC) to undergo colonoscopy surveillance instead of average-risk screening. However, these recommendations vary widely. ...
Background The currently known breast cancer-associated single nucleotide polymorphisms (SNPs) are presently not used to guide clinical management. We explored whether a genetic test that incorporates ...
Background: PMS2-associated Lynch syndrome is characterized by a relatively low colorectal cancer penetrance compared with other Lynch syndromes. However, age at colorectal cancer diagnosis varies widely, ...
Purpose: Biallelic pathogenic variants in the mismatch repair (MMR) genes cause a recessive childhood cancer predisposition syndrome known as constitutional mismatch repair deficiency (CMMRD). Family members ...
We present a novel method for the estimation of variance parameters in generalised linear mixed models. The method has its roots in Harville (J Am Stat Assoc 72(358):320–338, 1977)’s work, but it is able ...
When the same data are used to fit a model and estimate its predictive performance, this estimate may be optimistic, and its correction is required. The aim of this work is to compare the behaviour of ...
In this paper we consider a two-echelon supply chain with one supplier that controls a limited resource and a finite set of manufacturers who need to purchase this resource. We analyze the effect of the ...
Weight management strategies during pregnancy reduce child cardiometabolic risk. However, because maternal weight has an overall positive correlation with offspring bone mass, pregnancy weight management ...
Prevalences of overweight and obesity in young children have risen dramatically in the last several decades in most developed countries. Childhood overweight and obesity are known to have immediate and ...
Instrumental variable (IV) methods are widely used for estimating average treatment effects in the presence of unmeasured confounders. However, the capability of existing IV procedures, and most notably ...
A popular stochastic measure of the distance between the density of the lifetimes and its estimator is the integrated square error (ISE) and Hellinger distance (HD). In this paper, we focus on the right-censored ...
In this paper, we focus on the left-truncated and right-censored model, and construct the local linear and Nadaraya-Watson type estimators of the conditional density. Under suitable conditions, we establish ...
Objectives: Estimate the frequency of erectile dysfunction in patients with essential hypertension and associated variables, degree of control, cardiovascular risk and the impact on quality of life. Material ...
Background: Current HIV treatment guidelines recommend antiretroviral treatment (ART) initiation for all HIV-infected individuals regardless of CD4 count. This study evaluates the immunological and virological ...
Introduction: Osteoarthritis is the osteoarticular disease with the highest prevalence worldwide. In industrialized countries, 80% of the population > 65 years suffers from it. Objectives: To determine ...
Objective: To find autoantibodies (AAbs) in serum that could be useful to predict incidence of radiographic knee osteoarthritis (KOA). Design: A Nucleic-acid Programmable Protein Arrays (NAPPA) platform ...
In this paper, we consider a general regression model where missing data occur in the response and in the covariates. Our aim is to estimate the marginal distribution function and a marginal functional, ...
Goodness–of–fit tests for quantile regression models, in the presence of missing observations in the response variable, are introduced and analyzed in this paper. The different proposals are based on the ...
In this paper we present a method to forecast pollution episodes using measurements of the pollutant concentration along time. Specifically, we use a backfitting algorithm with local polynomial kernel ...
The one-parameter Bell family of distributions, introduced by Castellares et al. (Appl Math Model 56:172–185, 2018), is useful for modeling count data. This paper proposes and studies a goodness-of-fit ...
Multistate models can be successfully used for describing complex event history data, for example, describing stages in the disease progression of a patient. The so‐called “illness‐death” model plays a ...
Background: PMS2-associated Lynch syndrome is characterized by a relatively low colorectal cancer penetrance compared with other Lynch syndromes. However, age at colorectal cancer diagnosis varies widely, ...
Several aquatic living resources are overexploited. An example of this is a barnacle fishery, which is a commercial species that commands high prices in the market. We feel that not enough is known about ...
Background
The value of carotid intervention is predicated on long-term survival for patients to derive a stroke prevention benefit. Randomized trials report no significant difference in survival after ...
Objectives
To explore the diagnostic performance of circulating microRNAs (miRNAs) as biomarkers in patients with suspected stable coronary artery disease (CAD).
Methods
Plasma samples were collected ...
Epicardial adipose tissue (EAT) constitutes a novel parameter for cardiometabolic risk assessment and a target for therapy. Here, we evaluated for the first time the plasma microRNA (miRNA) profile as ...
Background The long-term effectiveness of atherectomy treatment for peripheral arterial disease is unknown. We studied 5-year clinical outcomes by endovascular treatment type among patients with peripheral ...
Objective:
To describe the long-term reintervention rate after endovascular abdominal aortic aneurysm repair (EVR), and identify factors predicting reintervention.
Summary of Background Data:
EVR is ...
Two‐stage instrumental variable methods are commonly used for estimating average causal effects in the presence of an unmeasured confounder. In the context of the proportional hazard Cox regression models, ...
Next‐generation sequencing (NGS) experiments are often performed in biomedical research nowadays, leading to methodological challenges related to the high‐dimensional and complex nature of the recorded ...
The Internet emerged as a powerful infrastructure for the worldwide communication and interaction of people. Some unethical uses of this technology (for instance spam or viruses) generated challenges in ...
In this research, an algorithm is presented for predicting the remaining useful life (RUL) of aircraft engines from a set of predictor variables measured by several sensors located in the engine. RUL prediction ...
The paper first introduces a new two-parameter continuous probability distribution
with bounded support from the extended exponential-geometric distribution. Closed-
form expressions are given for the ...
The problem of testing for the parametric form of the conditional variance is considered
in a fully nonparametric regression model. A test statistic based on a weighted
L2-distance between the empirical ...
We generalize a recent class of tests for univariate normality that are based on the empirical moment generating function to the multivariate setting, thus obtaining a class of affine invariant, consistent ...
We provide novel characterizations of multivariate normality that incorporate both the characteristic function and the moment generating function, and we employ these results to construct a class of affine ...
A test for the equality of error distributions in two nonparametric regression models is proposed. The test statistic is based on comparing the empirical characteristic functions of the residuals calculated ...
Auxiliary information x is commonly used in survey sampling at the estimation
stage. We propose an estimator of the finite population distribution function
Fy(t) when x is available for all units in ...
BACKGROUND: The optimal blood management after cardiac surgery remains controversial. Moreover, blood transfusions may have an impact on long-term outcomes.
OBJECTIVE: The aim of this study is to characterize ...
Introduction
Childhood obesity is of major public health concern with significant health, social and economic impacts, having even potential to reverse the increase in longevity that has been observed. ...
By applying the empirical likelihood method, we construct a new weighted estimator of the conditional mean function for a left-truncated and right-censored model. Assuming that the observations form a ...
Objective
Use logistic regression to determine a mathematical model which is able to predict injuries in aerobic gymnastics (AG) athletes, according to certain anthropometric characteristics.
Subjects ...
The aim of this study was to identify the differences between seasons in men´s water polo regular competition by analysing the changes of game-related statistics. The sample comprised 88 games from the ...
Accurate diagnosis of disease is of fundamental importance in clinical practice and medical research. Before a medical diagnostic test is routinely used in practice, its ability to distinguish between ...
OBJECTIVES: Estimate the frequency of erectile dysfunction in patients with essential hypertension and associated variables, degree of control, cardiovascular risk and the impact on quality of life.
MATERIAL ...