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1. Testing for superiority between two variance functions: (Publication); This paper focuses on the problem of testing the null hypothesis that the variance functions of two populations are equal versus one-sided alternatives under a general nonparametric heteroscedastic regression ...; Created on 16 September 2019
2. The role of the p-value in the multitesting problem: (Publication); Modern science frequently involves the analysis of large amount of quantitative information and the simultaneous testing of thousands or even hundreds of thousands null hypotheses. In this context, sometimes, ...; Created on 22 November 2019
3. Structural, Dermal and Ungual Characteristics of the Foot in Patients with Type II Diabetes: (Publication); Background and Objectives: Diabetes is a chronic and metabolic disease, considered as an important public health problem. The objective of this study was to determine the prevalence of podiatric pathology ...; Created on 20 November 2019
4. Effects of Family History on Relative and Absolute Risks for Colorectal Cancer: a Systematic Review and Meta-Analysis: (Publication); BACKGROUND & AIMS: Guidelines recommend individuals with familial colorectal cancer (FCC) to undergo colonoscopy surveillance instead of average-risk screening. However, these recommendations vary widely. ...; Created on 26 September 2019
5. Addition of a 161-SNP polygenic risk score to family history-based risk prediction: Impact on clinical management in non- BRCA1/2 breast cancer families: (Publication); Background The currently known breast cancer-associated single nucleotide polymorphisms (SNPs) are presently not used to guide clinical management. We explored whether a genetic test that incorporates ...; Created on 26 September 2019
6. The apparent genetic anticipation in PMS2-associated lynch syndrome families is explained by birth-cohort effect: (Publication); Background: PMS2-associated Lynch syndrome is characterized by a relatively low colorectal cancer penetrance compared with other Lynch syndromes. However, age at colorectal cancer diagnosis varies widely, ...; Created on 26 September 2019
7. Time trends in prevalence and incidence rates of childhood overweight and obesity in Portugal: Generation XXI birth cohort: (Publication); Childhood obesity estimates are steadily increasing worldwide. There is strong evidence that overweight children before puberty maintain this nutritional status for life. This study aimed to estimate the ...; Created on 25 September 2019
8. Time trends in prevalence and incidence rates of childhood overweight and obesity in Portugal: Generation XXI birth cohort: (Publication); Childhood obesity estimates are steadily increasing worldwide. There is strong evidence that overweight children before puberty maintain this nutritional status for life. This study aimed to estimate the ...; Created on 25 September 2019
9. Late HIV Diagnosis but Earlier Antiretroviral Treatment Initiation in Northwest Spain: Impact of Current Treatment Guidelines: (Publication); Background: Current HIV treatment guidelines recommend antiretroviral treatment (ART) initiation for all HIV-infected individuals regardless of CD4 count. This study evaluates the immunological and virological ...; Created on 24 September 2019
10. Prevalence of knee osteoarthritis in a random population sample in people aged 40 and over: (Publication); Introduction: Osteoarthritis is the osteoarticular disease with the highest prevalence worldwide. In industrialized countries, 80% of the population > 65 years suffers from it. Objectives: To determine ...; Created on 24 September 2019
11. Concordance between the Different Cardiovascular Risk Scores in People with Rheumatoid Arthritis and Psoriasis Arthritis: (Publication); Aim. To determine the cardiovascular risk and the concordance between the different scores in people with rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Methods. Observational descriptive study ...; Created on 24 September 2019
12. Discovery of an autoantibody signature for the early diagnosis of knee osteoarthritis: Data from the Osteoarthritis Initiative: (Publication); Objective: To find autoantibodies (AAbs) in serum that could be useful to predict incidence of radiographic knee osteoarthritis (KOA). Design: A Nucleic-acid Programmable Protein Arrays (NAPPA) platform ...; Created on 24 September 2019
13. A two-sample test for the equality of univariate marginal distributions for high-dimensional data: (Publication); A recurring theme in modern statistics is dealing with high-dimensional data whose main feature is a large number, p, of variables but a small sample size. In this context our aim is to address the problem ...; Created on 23 September 2019
14. Goodness-of-fit tests for quantile regression with missing responses: (Publication); Goodness–of–fit tests for quantile regression models, in the presence of missing observations in the response variable, are introduced and analyzed in this paper. The different proposals are based on the ...; Created on 19 September 2019
15. Goodness-of-fit tests for parametric specifications of conditionally heteroscedastic models: (Publication); We consider a goodness-of-fit test for certain parametrizations of conditionally heteroscedastic time series with unobserved components. Our test is quite general in that it can be employed to validate ...; Created on 17 September 2019
16. The apparent genetic anticipation effect in PMS2-associated Lynch syndrome families is explained by birth-cohort effect: (Publication); Background: PMS2-associated Lynch syndrome is characterized by a relatively low colorectal cancer penetrance compared with other Lynch syndromes. However, age at colorectal cancer diagnosis varies widely, ...; Created on 23 August 2019
17. Testing critical points of nonparametric regression curves: application to the management of stalked barnacles: (Publication); Several aquatic living resources are overexploited. An example of this is a barnacle fishery, which is a commercial species that commands high prices in the market. We feel that not enough is known about ...; Created on 23 August 2019
18. Plasma microRNA Profiling Reveals Novel Biomarkers of Epicardial Adipose Tissue: A Multidetector Computed Tomography Study: (Publication); Epicardial adipose tissue (EAT) constitutes a novel parameter for cardiometabolic risk assessment and a target for therapy. Here, we evaluated for the first time the plasma microRNA (miRNA) profile as ...; Created on 22 August 2019
19. Long-term Reintervention After Endovascular Abdominal Aortic Aneurysm Repair: (Publication); Objective: To describe the long-term reintervention rate after endovascular abdominal aortic aneurysm repair (EVR), and identify factors predicting reintervention. Summary of Background Data: EVR is ...; Created on 22 August 2019
20. Goodness-of-fit tests for disorder detection in NGS experiments: (Publication); Next‐generation sequencing (NGS) experiments are often performed in biomedical research nowadays, leading to methodological challenges related to the high‐dimensional and complex nature of the recorded ...; Created on 06 August 2019
21. A new semantic-based feature selection method for spam filtering: (Publication); The Internet emerged as a powerful infrastructure for the worldwide communication and interaction of people. Some unethical uses of this technology (for instance spam or viruses) generated challenges in ...; Created on 15 January 2019
22. Testing equality of a large number of densities under mixing conditions: (Publication); In certain settings, such as microarray data, the sampling information is formed by a large number of possibly dependent small data sets. In special applications, for example in order to perform clustering, ...; Created on 12 December 2018
23. A hybrid ARIMA–SVM model for the study of the remaining useful life of aircraft engines: (Publication); In this research, an algorithm is presented for predicting the remaining useful life (RUL) of aircraft engines from a set of predictor variables measured by several sensors located in the engine. RUL prediction ...; Created on 10 October 2018
24. Testing for the Poisson-Tweedie distribution: (Publication); In practice, count data exhibit over-dispersion, zero-inflation and even heavy tails. The Poisson–Tweedie distribution is a flexible parametric family able to accommodate these features. This paper proposes ...; Created on 09 October 2018
25. A model specification test for the variance function in nonparametric regression: (Publication); The problem of testing for the parametric form of the conditional variance is considered in a fully nonparametric regression model. A test statistic based on a weighted L2-distance between the empirical ...; Created on 09 October 2018
26. A new class of tests for multinormality with i.i.d. and garch data based on the empirical moment generating function: (Publication); We generalize a recent class of tests for univariate normality that are based on the empirical moment generating function to the multivariate setting, thus obtaining a class of affine invariant, consistent ...; Created on 09 October 2018
27. Characterization of multinormality and corresponding tests of fit, including for GARCH models: (Publication); We provide novel characterizations of multivariate normality that incorporate both the characteristic function and the moment generating function, and we employ these results to construct a class of affine ...; Created on 09 October 2018
28. Approximating the null distribution of a class of statistics for testing independence: (Publication); A class of tests for testing independence whose test statistic is an -norm of the difference between the joint empirical characteristic function and the product of the marginal empirical characteristic ...; Created on 09 October 2018
29. A two-sample test for the error distribution in nonparametric regression based on the characteristic function: (Publication); A test for the equality of error distributions in two nonparametric regression models is proposed. The test statistic is based on comparing the empirical characteristic functions of the residuals calculated ...; Created on 09 October 2018
30. Bootstrap-based testing approaches for the assessment of the diagnostic accuracy of biomarkers subject to a limit of detection: (Publication); Assessment of the diagnostic accuracy of biomarkers through receiver operating characteristic curve analysis frequently involves a limit of detection imposed by the laboratory analytical system precision. ...; Created on 09 October 2018
31. Parametric estimates for the receiver operating characteristic curve generalization for non-monotone relationships: (Publication); Diagnostic procedures are based on establishing certain conditions and then checking if those conditions are satisfied by a given individual. When the diagnostic procedure is based on a continuous marker, ...; Created on 22 May 2018
32. A Diagnostic Test Approach for Multitesting Problems: (Publication); In the last decades, multiple-testing problems have received much attention. Many different methods have been proposed in order to deal with this relevant issue. Most of them are focused on controlling ...; Created on 10 October 2018
33. Sequential double cross-validation for assessment of added predictive ability in high-dimensional OMIC applications: (Publication); Enriching existing predictive models with new biomolecular markers is an important task in the new multi-omic era. Clinical studies increasingly include new sets of omic measurements which may prove their ...; Created on 03 October 2018
34. Asymptotic distribution-free tests for semiparametric regressions with dependent data: (Publication); This article proposes a new general methodology for constructing nonparametric and semiparametric Asymptotically Distribution-Free (ADF) tests for semiparametric hypotheses in regression models for possibly ...; Created on 22 May 2018
35. Improving stability of prediction models based on correlated omics data by using network approaches: (Publication); Building prediction models based on complex omics datasets such as transcriptomics, proteomics, metabolomics remains a challenge in bioinformatics and biostatistics. Regularized regression techniques are ...; Created on 22 May 2018
36. Bootstrap-based procedures for inference in nonparametric receiver-operating characteristic curve regression analysis: (Publication); Prior to using a diagnostic test in a routine clinical setting, the rigorous evaluation of its diagnostic accuracy is essential. The receiver-operating characteristic curve is the measure of accuracy most ...; Created on 22 May 2018
37. On the estimation of the characteristic function in finite populations with applications: (Publication); This paper studies the estimation of the characteristic function of a finite population. Specifically, the weak convergence of the finite population empirical characteristic process is studied. Under suitable ...; Created on 14 May 2018
38. Computationally Efficient Goodness-of-Fit Tests for the Error Distribution in Nonparametric Regression: (Publication); Several procedures have been proposed for testing goodness-of-fit to the error distribution in nonparametric regression models. The null distribution of the associated test statistics is usually approximated ...; Created on 14 May 2018
39. Geographically Weighted Principal Components Analysis to assess diffuse pollution sources of soil heavy metal: Application to rough mountain areas in Northwest Spain.: (Publication); Heavy metal pollution can result in the degradation of the soil, air and water bodies' quality affecting the health of all living organism. We analyze the spatial distribution of the concentrations of ...; Created on 24 January 2018
40. Determining optimum wavelengths for leaf water content estimation from reflectance: A distance correlation approach: (Publication); This paper proposes a method to estimate leaf water content from reflectance in four commercial vineyard varieties by estimating the local maxima of a distance correlation function. First, it applies four ...; Created on 24 January 2018
41. Correcting for spatial heterogeneity in plant breeding experiments with P-splines: (Publication); An important aim of the analysis of agricultural field experiments is to obtain good predictions for genotypic performance, by correcting for spatial effects. In practice these corrections turn out to ...; Created on 24 January 2018
42. On the Combination of Omics Data for Prediction of Binary Outcomes: (Publication); Enrichment of predictive models with new biomolecular markers is an important task in high-dimensional omic applications. Increasingly, clinical studies include several sets of such omics markers available ...; Created on 10 October 2018
43. A weighted bootstrap approximation for comparing the error distributions in nonparametric regression: (Publication); Several procedures have been proposed for testing the equality of error distributions in two or more nonparametric regression models. Here we deal with methods based on comparing estimators of the cumulative ...; Created on 09 October 2018
44. Hábitos podológicos en personas con alteraciones ungueales: (Publication); Objective: To determine the prevalence of onychocryptosis and onychomycosis confirmed by culture in subjects attending a Podiatric University Hospital and to describe their podiatric habits. Method: ...; Created on 08 October 2018
45. An extended sequential goodness-of-fit multiple testing method for discrete data: (Publication); The sequential goodness-of-fit (SGoF) multiple testing method has recently been proposed as an alternative to the familywise error rate-And the false discovery rate-controlling procedures in high-dimensional ...; Created on 23 January 2018
46. Clinical experience with the integrase inhibitors Dolutegravir and Elvitegravir in HIV-infected patients: Efficacy, safety and tolerance: (Publication); Two integrase inhibitors (INSTIs), dolutegravir (DTG) and elvitegravir/cobicistat (EVG/COBI), have joined recently the pharmacotherapy arsenal against HIV. This study evaluated the efficacy and tolerability ...; Created on 19 September 2017
47. Highly sensitive marker panel for guidance in Lung Cancer Rapid Diagnostic Units: (Publication); While evidence for lung cancer screening implementation in Europe is awaited, Rapid Diagnostic Units have been established in many hospitals to accelerate the early diagnosis of lung cancer. We seek to ...; Created on 18 September 2017
48. Modelling spatial trends in sorghum breeding field trials using a two-dimensional P-spline mixed model: (Publication); Adjustment for spatial trends in plant breeding field trials is essential for efficient evaluation and selection of genotypes. Current mixed model methods of spatial analysis are based on a multi-step ...; Created on 18 September 2017
49. Assessing planar asymmetries in shipbuilding from point clouds: (Publication); This paper introduces a statistical methodology to identify planar asymmetries in surfaces. An algorithm based on bivariate kernel smoothers is used to estimate non-parametrically the surface from a point ...; Created on 18 September 2017
50. Measuring the efficiency of the Spanish Olympic Sports Federations: (Publication); Research question: The most common result in the analysis of efficiency in multisport competitions like the Olympic Games using the data envelopment analysis (DEA) is a ranking of the participating countries. ...; Created on 18 September 2017