Background and Objectives: Diabetes is a chronic and metabolic disease, considered as an important public health problem. The objective of this study was to determine the prevalence of podiatric pathology ...
BACKGROUND & AIMS: Guidelines recommend individuals with familial colorectal cancer (FCC) to undergo colonoscopy surveillance instead of average-risk screening. However, these recommendations vary widely. ...
Background The currently known breast cancer-associated single nucleotide polymorphisms (SNPs) are presently not used to guide clinical management. We explored whether a genetic test that incorporates ...
Childhood obesity estimates are steadily increasing worldwide. There is strong evidence that overweight children before puberty maintain this nutritional status for life. This study aimed to estimate the ...
Childhood obesity estimates are steadily increasing worldwide. There is strong evidence that overweight children before puberty maintain this nutritional status for life. This study aimed to estimate the ...
Multivariate response data often arise in practice and they are frequently subject to missingness. Under this circumstance, the standard sufficient dimension reduction (SDR) methods cannot be used directly. ...
Background: Current HIV treatment guidelines recommend antiretroviral treatment (ART) initiation for all HIV-infected individuals regardless of CD4 count. This study evaluates the immunological and virological ...
Introduction: Osteoarthritis is the osteoarticular disease with the highest prevalence worldwide. In industrialized countries, 80% of the population > 65 years suffers from it. Objectives: To determine ...
Aim. To determine the cardiovascular risk and the concordance between the different scores in people with rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Methods. Observational descriptive study ...
Objective: To find autoantibodies (AAbs) in serum that could be useful to predict incidence of radiographic knee osteoarthritis (KOA). Design: A Nucleic-acid Programmable Protein Arrays (NAPPA) platform ...
A recurring theme in modern statistics is dealing with high-dimensional data whose main feature is a large number, p, of variables but a small sample size. In this context our aim is to address the problem ...
Goodness–of–fit tests for quantile regression models, in the presence of missing observations in the response variable, are introduced and analyzed in this paper. The different proposals are based on the ...
Several aquatic living resources are overexploited. An example of this is a barnacle fishery, which is a commercial species that commands high prices in the market. We feel that not enough is known about ...
Epicardial adipose tissue (EAT) constitutes a novel parameter for cardiometabolic risk assessment and a target for therapy. Here, we evaluated for the first time the plasma microRNA (miRNA) profile as ...
Objective:
To describe the long-term reintervention rate after endovascular abdominal aortic aneurysm repair (EVR), and identify factors predicting reintervention.
Summary of Background Data:
EVR is ...
Next‐generation sequencing (NGS) experiments are often performed in biomedical research nowadays, leading to methodological challenges related to the high‐dimensional and complex nature of the recorded ...
The Internet emerged as a powerful infrastructure for the worldwide communication and interaction of people. Some unethical uses of this technology (for instance spam or viruses) generated challenges in ...
In this research, an algorithm is presented for predicting the remaining useful life (RUL) of aircraft engines from a set of predictor variables measured by several sensors located in the engine. RUL prediction ...
Diagnostic procedures are based on establishing certain conditions and then checking if those conditions are satisfied by a given individual. When the diagnostic procedure is based on a continuous marker, ...
Enriching existing predictive models with new biomolecular markers is an important task in the new multi-omic era. Clinical studies increasingly include new sets of omic measurements which may prove their ...
... typically used to deal with the high dimensionality of these datasets. However, due to the presence of correlation in the datasets, it is difficult to select the best model and application of these methods ...
Heavy metal pollution can result in the degradation of the soil, air and water bodies' quality affecting the health of all living organism. We analyze the spatial distribution of the concentrations of ...
Enrichment of predictive models with new biomolecular markers is an important task in high-dimensional omic applications. Increasingly, clinical studies include several sets of such omics markers available ...
Objective: To determine the prevalence of onychocryptosis and onychomycosis confirmed by culture in subjects attending a Podiatric University Hospital and to describe their podiatric habits.
Method: ...
The sequential goodness-of-fit (SGoF) multiple testing method has recently been proposed as an alternative to the familywise error rate-And the false discovery rate-controlling procedures in high-dimensional ...
Two integrase inhibitors (INSTIs), dolutegravir (DTG) and elvitegravir/cobicistat (EVG/COBI), have joined recently the pharmacotherapy arsenal against HIV. This study evaluated the efficacy and tolerability ...
While evidence for lung cancer screening implementation in Europe is awaited, Rapid Diagnostic Units have been established in many hospitals to accelerate the early diagnosis of lung cancer. We seek to ...
Research question: The most common result in the analysis of efficiency in multisport competitions like the Olympic Games using the data envelopment analysis (DEA) is a ranking of the participating countries. ...
Background: Tumor budding is a readily detectable histopathologic feature that has been recognized as an adverse prognostic factor in several human cancers.
Objective: We sought to assess the correlation ...
Background: The high prevalence of cardiovascular risk factors among the renal transplant population accounts for increased mortality. The aim of this study is to determine the incidence of cardiovascular ...
The aim of this study was to identify specific offensive performance indicators that distinguish the top clubs from the others in the Male Honour Division of the Spanish Water Polo League. A total of 88 ...
Deformations in tunnels and galleries due to confinement pressures can occur continuously but also at discrete time intervals. We propose a methodology to detect discrete significant deformations in tunnels ...
Objective: To determine whether high levels of mid-regional pro-atrial natriuretic peptide (MR-proANP), copeptin, and procalcitonin (PCT) plasma concentrations are associated with increased mortality risk.
Methods: ...
For the high-dimensional partially linear varying coefficient models where covariates in the nonparametric part are measured with additive errors, we, in this paper, study asymptotic distributions of a ...
The PI3K/AKT/mTOR signaling pathway has emerged as one of the most frequently deregulated in head and neck squamous cell carcinomas (HNSCC). Numerous alterations of various upstream and downstream components ...
More than 90% of the sulfur dioxide in the air comes from human sources. Because of the adverse health effects of high levels of sulfur dioxide, specific regulations have been adopted to manage and reduce ...
In the field of multiple comparison procedures, adjusted p-values are an important tool to evaluate the significance of a test statistic while taking the multiplicity into account. In this paper, we introduce ...
Introduction: Acute kidney injury (AKI) is a severe complication in critically ill children. The aim of the study was to describe the characteristics of AKI, as well as to analyse the prognostic factors ...
Abnormalities in serum phosphorus, calcium and parathyroid hormone (PTH) have been associated with poor survival in haemodialysis patients. This COSMOS (Current management Of Secondary hyperparathyroidism: ...
Background Ventricular fibrillation (VF) has been proposed to be maintained by localized high-frequency sources. We tested whether spectral-phase analysis of the precordial ECG enabled identification of ...
IntroductionThe differential diagnosis of malignant and tuberculous pleural effusion is frequently difficult.
ObjectivesThe aim of our study is to determine the discrimination value of demographic ...
While moderate acute exercise has been associated with strong anti-inflammatory mechanisms, strenuous exercise has been linked to deleterious inflammatory perturbations. It is therefore fundamental to ...
The suitability of a total-length-based, minimum capture-size and different protection regimes was investigated for the gooseneck barnacle Pollicipes pollicipes shellfishery in N Spain. For this analysis, ...
The benefit of azacitidine treatment in survival of high-risk myelodysplastic syndromes (MDS) patients compared with conventional care treatment (CCT) has not been established outside clinical trials. ...
We propose a new methodology to assess whether the shape of a measured object fits a known surface. The method is based on calculating uncertainty spheres for a specific confidence level obtained by kernel ...
In lightning-induced fire risk prediction models, the number of potential predictors is usually high, with some redundancy among them. It is therefore important to select the best subset of predictors ...
When working with high-dimensional biological data the so-called multiple hypothesis testing problem emerges. That is, when many separate tests are performed, several will be significant by chance provoking ...
A question that tends to arise in multiple regression models (with p variables), and that has not been totally satisfactory solved, is to determine the best subset or subsets of q q≤p) predictors which ...
A question that tends to arise in multiple regression models (with p variables), and that has not been totally satisfactory solved, is to determine the best subset or subsets of q q≤p) predictors which ...