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1. Assessment of assumptions of statistical analysis methods in randomised clinical trials: the what and how: (Publication); When analysing and presenting results ofrandomised clinical trials, trialists rarely report if or how underlying statisticalassumptions were validated. To avoid data-driven biased trial results, it should ...; Created on 29 January 2020
2. Testing for superiority between two variance functions: (Publication); This paper focuses on the problem of testing the null hypothesis that the variance functions of two populations are equal versus one-sided alternatives under a general nonparametric heteroscedastic regression ...; Created on 16 September 2019
3. Traditional Processed Meat Products Re-designed Towards Inulin-rich Functional Foods Reduce Polyps in Two Colorectal Cancer Animal Models: (Publication); Inulin-rich foods exert a prebiotic effect, as this polysaccharide is able to enhance beneficial colon microbiota populations, giving rise to the in situ production of short-chain fatty acids (SCFAs) such ...; Created on 22 November 2019
4. Addition of a 161-SNP polygenic risk score to family history-based risk prediction: Impact on clinical management in non- BRCA1/2 breast cancer families: (Publication); Background The currently known breast cancer-associated single nucleotide polymorphisms (SNPs) are presently not used to guide clinical management. We explored whether a genetic test that incorporates ...; Created on 26 September 2019
5. On the estimation of variance parameters in non-standard generalised linear mixed models: application to penalised smoothing: (Publication); We present a novel method for the estimation of variance parameters in generalised linear mixed models. The method has its roots in Harville (J Am Stat Assoc 72(358):320–338, 1977)’s work, but it is able ...; Created on 25 September 2019
6. Time trends in prevalence and incidence rates of childhood overweight and obesity in Portugal: Generation XXI birth cohort: (Publication); Childhood obesity estimates are steadily increasing worldwide. There is strong evidence that overweight children before puberty maintain this nutritional status for life. This study aimed to estimate the ...; Created on 25 September 2019
7. Gestational Weight Gain and Offspring Bone Mass: Different Associations in Healthy Weight Versus Overweight Women: (Publication); Weight management strategies during pregnancy reduce child cardiometabolic risk. However, because maternal weight has an overall positive correlation with offspring bone mass, pregnancy weight management ...; Created on 25 September 2019
8. Time trends in prevalence and incidence rates of childhood overweight and obesity in Portugal: Generation XXI birth cohort: (Publication); Childhood obesity estimates are steadily increasing worldwide. There is strong evidence that overweight children before puberty maintain this nutritional status for life. This study aimed to estimate the ...; Created on 25 September 2019
9. Adjusting for bias introduced by instrumental variable estimation in the Cox proportional hazards model: (Publication); Instrumental variable (IV) methods are widely used for estimating average treatment effects in the presence of unmeasured confounders. However, the capability of existing IV procedures, and most notably ...; Created on 25 September 2019
10. A two-sample test for the equality of univariate marginal distributions for high-dimensional data: (Publication); A recurring theme in modern statistics is dealing with high-dimensional data whose main feature is a large number, p, of variables but a small sample size. In this context our aim is to address the problem ...; Created on 23 September 2019
11. Goodness-of-fit tests for quantile regression with missing responses: (Publication); Goodness–of–fit tests for quantile regression models, in the presence of missing observations in the response variable, are introduced and analyzed in this paper. The different proposals are based on the ...; Created on 19 September 2019
12. Predicting pollution incidents through semiparametric quantile regression models: (Publication); In this paper we present a method to forecast pollution episodes using measurements of the pollutant concentration along time. Specifically, we use a backfitting algorithm with local polynomial kernel ...; Created on 18 September 2019
13. Goodness-of-fit tests for parametric specifications of conditionally heteroscedastic models: (Publication); We consider a goodness-of-fit test for certain parametrizations of conditionally heteroscedastic time series with unobserved components. Our test is quite general in that it can be employed to validate ...; Created on 17 September 2019
14. On goodness-of-fit tests for the Bell distribution: (Publication); The one-parameter Bell family of distributions, introduced by Castellares et al. (Appl Math Model 56:172–185, 2018), is useful for modeling count data. This paper proposes and studies a goodness-of-fit ...; Created on 17 September 2019
15. Estimation in the progressive illness-death model: a non-exhaustive review: (Publication); Multistate models can be successfully used for describing complex event history data, for example, describing stages in the disease progression of a patient. The so‐called “illness‐death” model plays a ...; Created on 23 August 2019
16. A method for determining groups in multiple survival curves: (Publication); Survival analysis includes a wide variety of methods for analyzing time‐to‐event data. One basic but important goal in survival analysis is the comparison of survival curves between groups. Several nonparametric ...; Created on 23 August 2019
17. Systematic review with meta‐analysis: risk factors for recurrent primary sclerosing cholangitis after liver transplantation: (Publication); Background After liver transplantation primary sclerosing cholangitis (PSC), the condition returns in the transplanted liver in a subset of patients (recurrent primary sclerosing cholangitis, rPSC). Aim To ...; Created on 23 August 2019
18. Testing critical points of nonparametric regression curves: application to the management of stalked barnacles: (Publication); Several aquatic living resources are overexploited. An example of this is a barnacle fishery, which is a commercial species that commands high prices in the market. We feel that not enough is known about ...; Created on 23 August 2019
19. Adverse Events After Atherectomy: Analyzing Long‐Term Outcomes of Endovascular Lower Extremity Revascularization Techniques: (Publication); Background The long-term effectiveness of atherectomy treatment for peripheral arterial disease is unknown. We studied 5-year clinical outcomes by endovascular treatment type among patients with peripheral ...; Created on 22 August 2019
20. Long-term Reintervention After Endovascular Abdominal Aortic Aneurysm Repair: (Publication); Objective: To describe the long-term reintervention rate after endovascular abdominal aortic aneurysm repair (EVR), and identify factors predicting reintervention. Summary of Background Data: EVR is ...; Created on 22 August 2019
21. External Validation and Recalculation of the CODEX Index in COPD Patients. A 3CIAplus Cohort Study: (Publication); The CODEX index was developed and validated in patients hospitalized for COPD exacerbation to predict the risk of death and readmission within one year after discharge. Our study aimed to validate the ...; Created on 22 August 2019
22. Goodness-of-fit tests for disorder detection in NGS experiments: (Publication); Next‐generation sequencing (NGS) experiments are often performed in biomedical research nowadays, leading to methodological challenges related to the high‐dimensional and complex nature of the recorded ...; Created on 06 August 2019
23. Testing equality of a large number of densities under mixing conditions: (Publication); In certain settings, such as microarray data, the sampling information is formed by a large number of possibly dependent small data sets. In special applications, for example in order to perform clustering, ...; Created on 12 December 2018
24. Testing for the Poisson-Tweedie distribution: (Publication); In practice, count data exhibit over-dispersion, zero-inflation and even heavy tails. The Poisson–Tweedie distribution is a flexible parametric family able to accommodate these features. This paper proposes ...; Created on 09 October 2018
25. A model specification test for the variance function in nonparametric regression: (Publication); The problem of testing for the parametric form of the conditional variance is considered in a fully nonparametric regression model. A test statistic based on a weighted L2-distance between the empirical ...; Created on 09 October 2018
26. A new class of tests for multinormality with i.i.d. and garch data based on the empirical moment generating function: (Publication); We generalize a recent class of tests for univariate normality that are based on the empirical moment generating function to the multivariate setting, thus obtaining a class of affine invariant, consistent ...; Created on 09 October 2018
27. Characterization of multinormality and corresponding tests of fit, including for GARCH models: (Publication); We provide novel characterizations of multivariate normality that incorporate both the characteristic function and the moment generating function, and we employ these results to construct a class of affine ...; Created on 09 October 2018
28. Approximating the null distribution of a class of statistics for testing independence: (Publication); A class of tests for testing independence whose test statistic is an -norm of the difference between the joint empirical characteristic function and the product of the marginal empirical characteristic ...; Created on 09 October 2018
29. A two-sample test for the error distribution in nonparametric regression based on the characteristic function: (Publication); A test for the equality of error distributions in two nonparametric regression models is proposed. The test statistic is based on comparing the empirical characteristic functions of the residuals calculated ...; Created on 09 October 2018
30. Parametric estimates for the receiver operating characteristic curve generalization for non-monotone relationships: (Publication); Diagnostic procedures are based on establishing certain conditions and then checking if those conditions are satisfied by a given individual. When the diagnostic procedure is based on a continuous marker, ...; Created on 22 May 2018
31. Body mass index transitions during childhood: a multiple-state model approach: (Publication); Introduction Childhood obesity is of major public health concern with significant health, social and economic impacts, having even potential to reverse the increase in longevity that has been observed. ...; Created on 06 March 2019
32. Bayesian nonparametric inference for the covariate-adjusted ROC curve: (Publication); Accurate diagnosis of disease is of fundamental importance in clinical practice and medical research. Before a medical diagnostic test is routinely used in practice, its ability to distinguish between ...; Created on 10 October 2018
33. nsROC: An R package for non-standard ROC curve analysis: (Publication); The receiver operating characteristic (ROC) curve is a graphical method which has become standard in the analysis of diagnostic markers, that is, in the study of the classiﬁcation ability of a numerical ...; Created on 10 October 2018
34. A Diagnostic Test Approach for Multitesting Problems: (Publication); In the last decades, multiple-testing problems have received much attention. Many different methods have been proposed in order to deal with this relevant issue. Most of them are focused on controlling ...; Created on 10 October 2018
35. Predictive factors of satisfaction and quality of life after immediate breast reconstruction using the BREAST-Q: (Publication); Aims and objectives: To analyse quality of life and satisfaction after immediate breast reconstruction due to cancer and its determining factors. Background: Studying breast reconstruction is important ...; Created on 08 October 2018
36. Comments on "One-tailed asymptotic inferences for the difference of proportions: analysis of 97 methods of inference" by Alvarez Hernandez M, Martin Andres A and Herranz Tejedor I. (2018): (Publication); Two-tailed asymptotic inferences for the difference d = p2 − p1 with independent proportions have been widely studied in the literature. Nevertheless, the case of one tail has received less attention, ...; Created on 03 October 2018
37. Sequential double cross-validation for assessment of added predictive ability in high-dimensional OMIC applications: (Publication); Enriching existing predictive models with new biomolecular markers is an important task in the new multi-omic era. Clinical studies increasingly include new sets of omic measurements which may prove their ...; Created on 03 October 2018
38. On the estimation of variance parameters in non-standard generalised linear mixed models: application to penalised smoothing: (Publication); We present a novel method for the estimation of variance parameters in generalised linear mixed models. The method has its roots in Harville (J Am Stat Assoc 72(358):320–338, 1977)’s work, but it is able ...; Created on 02 October 2018
39. MUL plus DO: a multicomponent index for the quick diagnosis of peritonitis in peritoneal dialysis patients: (Publication); Peritoneal infection is a common problem that has a negative impact on the survival of patients and the technique. The early administration of peritoneal infection treatment reduces complications. The ...; Created on 01 October 2018
40. Penalized profile least squares-based statistical inference for varying coefficient partially linear errors-in-variables models: (Publication); The purpose of this paper is two fold. First, we investigate estimation for varying coefficient partially linear models in which covariates in the nonparametric part are measured with errors. As there ...; Created on 01 October 2018
41. Minimum Penalized phi-Divergence Estimation under Model Misspecification: (Publication); This paper focuses on the consequences of assuming a wrong model for multinomial data when using minimum penalized phi-divergence, also known as minimum penalized disparity estimators, to estimate the ...; Created on 01 October 2018
42. Bootstrap-based procedures for inference in nonparametric receiver-operating characteristic curve regression analysis: (Publication); Prior to using a diagnostic test in a routine clinical setting, the rigorous evaluation of its diagnostic accuracy is essential. The receiver-operating characteristic curve is the measure of accuracy most ...; Created on 22 May 2018
43. Levels of anti-CMV antibodies are modulated by the frequency and intensity of virus reactivations in kidney transplant patients: (Publication); Anti-CMV (cytomegalovirus) antibody titers are related to immune alterations and increased risk of mortality. To test whether they represent a marker of infection history, we analyzed the effect of viral ...; Created on 22 May 2018
44. Large-scale external validation and comparison of prognostic models: an application to chronic obstructive pulmonary disease: (Publication); Background: External validations and comparisons of prognostic models or scores are a prerequisite for their use in routine clinical care but are lacking in most medical fields including chronic obstructive ...; Created on 22 May 2018
45. Computationally Efficient Goodness-of-Fit Tests for the Error Distribution in Nonparametric Regression: (Publication); Several procedures have been proposed for testing goodness-of-fit to the error distribution in nonparametric regression models. The null distribution of the associated test statistics is usually approximated ...; Created on 14 May 2018
46. Inverse Probability Weighted Cox Regression for Doubly Truncated Data: (Publication); Doubly truncated data arise when event times are observed only if they fall within subject-specific, possibly random, intervals. While non-parametric methods for survivor function estimation using doubly ...; Created on 20 February 2018
47. Determining optimum wavelengths for leaf water content estimation from reflectance: A distance correlation approach: (Publication); This paper proposes a method to estimate leaf water content from reflectance in four commercial vineyard varieties by estimating the local maxima of a distance correlation function. First, it applies four ...; Created on 24 January 2018
48. Adjusting for bias introduced by instrumental variable estimation in the Cox proportional hazards model: (Publication); Instrumental variable (IV) methods are widely used for estimating average treatment effects in the presence of unmeasured confounders. However, the capability of existing IV procedures, and most notably ...; Created on 10 October 2018
49. A weighted bootstrap approximation for comparing the error distributions in nonparametric regression: (Publication); Several procedures have been proposed for testing the equality of error distributions in two or more nonparametric regression models. Here we deal with methods based on comparing estimators of the cumulative ...; Created on 09 October 2018
50. Low-voltage chest CT: another way to reduce the radiation dose in asbestos-exposed patients: (Publication); AIM: To assess whether low voltage chest computed tomography (CT) can be used to successfully diagnose disease in patients with asbestos exposure. MATERIALS AND METHODS: Fifty-six former employees ...; Created on 22 May 2018