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1. Assessment of assumptions of statistical analysis methods in randomised clinical trials: the what and how: (Publication); When analysing and presenting results ofrandomised clinical trials, trialists rarely report if or how underlying statisticalassumptions were validated. To avoid data-driven biased trial results, it should ...; Created on 29 January 2020
2. On the estimation of variance parameters in non-standard generalised linear mixed models: application to penalised smoothing: (Publication); We present a novel method for the estimation of variance parameters in generalised linear mixed models. The method has its roots in Harville (J Am Stat Assoc 72(358):320–338, 1977)’s work, but it is able ...; Created on 25 September 2019
3. Time trends in prevalence and incidence rates of childhood overweight and obesity in Portugal: Generation XXI birth cohort: (Publication); Childhood obesity estimates are steadily increasing worldwide. There is strong evidence that overweight children before puberty maintain this nutritional status for life. This study aimed to estimate the ...; Created on 25 September 2019
4. Time trends in prevalence and incidence rates of childhood overweight and obesity in Portugal: Generation XXI birth cohort: (Publication); Childhood obesity estimates are steadily increasing worldwide. There is strong evidence that overweight children before puberty maintain this nutritional status for life. This study aimed to estimate the ...; Created on 25 September 2019
5. Adjusting for bias introduced by instrumental variable estimation in the Cox proportional hazards model: (Publication); Instrumental variable (IV) methods are widely used for estimating average treatment effects in the presence of unmeasured confounders. However, the capability of existing IV procedures, and most notably ...; Created on 25 September 2019
6. Five-year reintervention after endovascular abdominal aortic aneurysm repair in the Vascular Quality Initiative: (Publication); Objective: Patients who undergo endovascular abdominal aortic aneurysm repair (EVR) remain at risk for reintervention and rupture. We sought to define the 5-year rate of reintervention and rupture after ...; Created on 25 September 2019
7. Discovery of an autoantibody signature for the early diagnosis of knee osteoarthritis: Data from the Osteoarthritis Initiative: (Publication); Objective: To find autoantibodies (AAbs) in serum that could be useful to predict incidence of radiographic knee osteoarthritis (KOA). Design: A Nucleic-acid Programmable Protein Arrays (NAPPA) platform ...; Created on 24 September 2019
8. Estimation in the progressive illness-death model: a non-exhaustive review: (Publication); Multistate models can be successfully used for describing complex event history data, for example, describing stages in the disease progression of a patient. The so‐called “illness‐death” model plays a ...; Created on 23 August 2019
9. A method for determining groups in <span class="highlight">multiple survival curves</span> ...: (Publication); Survival analysis includes a wide variety of methods for analyzing time‐to‐event data. One basic but important goal in survival analysis is the comparison of survival curves between groups. Several nonparametric ...; Created on 23 August 2019
10. Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait: (Publication); Survival to extreme ages clusters within families. However, identifying genetic loci conferring longevity and low morbidity in such longevous families is challenging. There is debate concerning the survival ...; Created on 23 August 2019
11. Systematic review with meta‐analysis: risk factors for recurrent primary sclerosing cholangitis after liver transplantation: (Publication); Background After liver transplantation primary sclerosing cholangitis (PSC), the condition returns in the transplanted liver in a subset of patients (recurrent primary sclerosing cholangitis, rPSC). Aim To ...; Created on 23 August 2019
12. Testing critical points of nonparametric regression curves: application to the management of stalked barnacles: (Publication); Several aquatic living resources are overexploited. An example of this is a barnacle fishery, which is a commercial species that commands high prices in the market. We feel that not enough is known about ...; Created on 23 August 2019
13. A comparative analysis of long-term mortality after carotid endarterectomy and carotid stenting: (Publication); Background The value of carotid intervention is predicated on long-term survival for patients to derive a stroke prevention benefit. Randomized trials report no significant difference in survival after ...; Created on 22 August 2019
14. Long-term Reintervention After Endovascular Abdominal Aortic Aneurysm Repair: (Publication); Objective: To describe the long-term reintervention rate after endovascular abdominal aortic aneurysm repair (EVR), and identify factors predicting reintervention. Summary of Background Data: EVR is ...; Created on 22 August 2019
15. Comment on ‘Baseline patients’ characteristics as predictors for therapeutic survival and response in patients with psoriasis on biological treatments': (Publication); Created on 22 August 2019
16. External Validation and Recalculation of the CODEX Index in COPD Patients. A 3CIAplus Cohort Study: (Publication); The CODEX index was developed and validated in patients hospitalized for COPD exacerbation to predict the risk of death and readmission within one year after discharge. Our study aimed to validate the ...; Created on 22 August 2019
17. Lectin-like transcript 1 (LLT1) expression is associated with nodal metastasis in patients with head and neck cutaneous squamous cell carcinoma: (Publication); The interaction of lectin-like transcript 1 (LLT1) with CD161 inhibits Natural Killer cell activation. Overexpression of LLT1 contributes to the immunosuppressive properties of tumor cells. However, there ...; Created on 22 August 2019
18. Goodness-of-fit tests for disorder detection in NGS experiments: (Publication); Next‐generation sequencing (NGS) experiments are often performed in biomedical research nowadays, leading to methodological challenges related to the high‐dimensional and complex nature of the recorded ...; Created on 06 August 2019
19. Serum phosphate optimal timing and range associated with patients survival in haemodialysis: the COSMOS study: (Publication); Background Serum phosphate is a key parameter in the management of chronic kidney disease-mineral and bone disorder (CKD-MBD). The timing of phosphate measurement is not standardized in the current guidelines. ...; Created on 10 October 2018
20. Body mass index transitions during childhood: a multiple-state model approach: (Publication); Introduction Childhood obesity is of major public health concern with significant health, social and economic impacts, having even potential to reverse the increase in longevity that has been observed. ...; Created on 06 March 2019
21. Percentile curves and reference values for 2000-m rowing ergometer performance time in international rowers aged 14-70 years: (Publication); The aim of this study was to provide percentile curves and reference values for the performance in 2000-m maximal effort on rowing ergometer. A cross-sectional study was carried out with a non-probabilistic ...; Created on 11 October 2018
22. Bayesian nonparametric inference for the covariate-adjusted ROC curve: (Publication); Accurate diagnosis of disease is of fundamental importance in clinical practice and medical research. Before a medical diagnostic test is routinely used in practice, its ability to distinguish between ...; Created on 10 October 2018
23. A Diagnostic Test Approach for Multitesting Problems: (Publication); In the last decades, multiple-testing problems have received much attention. Many different methods have been proposed in order to deal with this relevant issue. Most of them are focused on controlling ...; Created on 10 October 2018
24. Longevity Around the Turn of the 20th Century: Life-Long Sustained Survival Advantage for Parents of Today's Nonagenarians.: (Publication); Members of longevous families live longer than individuals from similar birth cohorts and delay/escape age-related diseases. Insight into this familial component of longevity can provide important knowledge ...; Created on 03 October 2018
25. On the estimation of variance parameters in non-standard generalised linear mixed models: application to penalised smoothing: (Publication); We present a novel method for the estimation of variance parameters in generalised linear mixed models. The method has its roots in Harville (J Am Stat Assoc 72(358):320–338, 1977)’s work, but it is able ...; Created on 02 October 2018
26. Efficient nonparametric confidence bands for receiver operating-characteristic curves: (Publication); Receiver operating-characteristic curve is a popular graphical method frequently used in order to study the diagnostic capacity of continuous (bio)markers. In spite of the existence of a huge number of ...; Created on 01 October 2018
27. MUL plus DO: a multicomponent index for the quick diagnosis of peritonitis in peritoneal dialysis patients: (Publication); Peritoneal infection is a common problem that has a negative impact on the survival of patients and the technique. The early administration of peritoneal infection treatment reduces complications. The ...; Created on 01 October 2018
28. Estimation of monotone bivariate quantile residual life: (Publication); The bivariate quantile residual life function can play an important role in statistical reliability and survival analysis. In many situations assuming a decreasing form for it is recommended. Here, we ...; Created on 28 September 2018
29. Survival analysis with delayed entry in selected families with application to human longevity: (Publication); In the field of aging research, family-based sampling study designs are commonly used to study the lifespans of long-lived family members. However, the specific sampling procedure should be carefully taken ...; Created on 22 May 2018
30. Large-scale external validation and comparison of prognostic models: an application to chronic obstructive pulmonary disease: (Publication); Background: External validations and comparisons of prognostic models or scores are a prerequisite for their use in routine clinical care but are lacking in most medical fields including chronic obstructive ...; Created on 22 May 2018
31. Smooth time-dependent receiver operating characteristic curve estimators: (Publication); The receiver operating characteristic curve is a popular graphical method often used to study the diagnostic capacity of continuous (bio)markers. When the considered outcome is a time-dependent variable, ...; Created on 22 May 2018
32. Nonparametric Estimation of Transition Probabilities for a General Progressive Multi-State Model Under CrossSectional Sampling: (Publication); Nonparametric estimation of the transition probability matrix of a progressive multi-state model is consideredunder cross-sectional sampling. Two diﬀerent estimators adapted to possibly right-censored ...; Created on 20 February 2018
33. Inverse Probability Weighted Cox Regression for Doubly Truncated Data: (Publication); Doubly truncated data arise when event times are observed only if they fall within subject-specific, possibly random, intervals. While non-parametric methods for survivor function estimation using doubly ...; Created on 20 February 2018
34. A weighted estimator of conditional hazard rate with left-truncated and dependent data: (Publication); Based on empirical likelihood method, we construct new weighted estimators of conditional density and conditional survival functions when the interest random variable is subject to random left-truncation; ...; Created on 24 January 2018
35. Adjusting for bias introduced by instrumental variable estimation in the Cox proportional hazards model: (Publication); Instrumental variable (IV) methods are widely used for estimating average treatment effects in the presence of unmeasured confounders. However, the capability of existing IV procedures, and most notably ...; Created on 10 October 2018
36. Nonparametric estimation of an event-free survival distribution under cross-sectional sampling: (Publication); Created on 02 August 2018
37. An extended sequential goodness-of-fit multiple testing method for discrete data: (Publication); The sequential goodness-of-fit (SGoF) multiple testing method has recently been proposed as an alternative to the familywise error rate-And the false discovery rate-controlling procedures in high-dimensional ...; Created on 23 January 2018
38. Copula-graphic estimation with left-truncated and right-censored data: (Publication); In Survival Analysis and related fields of research right-censored and left-truncated data often appear. Usually, it is assumed that the right-censoring variable is independent of the lifetime of ultimate ...; Created on 23 January 2018
39. Long-Term Survival After Carotid Endarterectomy and Carotid Stenting: A Propensity-Matched Analysis: (Publication); Survival after carotid endarterectomy (CEA) and carotid artery stenting (CAS) is required for patients to derive a stroke prevention benefit. Randomized trials report no difference, whereas observational ...; Created on 23 January 2018
40. Comparison of two discrimination indexes in the categorisation of continuous predictors in time-to-event studies: (Publication); The Cox proportionalhazards model is the most widely used survival predictionmodel for analysing time-to-event data. To measure the discrimination ability of a survival model the concordance probability ...; Created on 18 September 2017
41. npregfast: an R package for nonparametric estimation and inference in life sciences: (Publication); We present the R npregfast package via some applications involved with the study of living organisms. The package implements nonparametric estimation procedures in regression models with or without factor-by-curve ...; Created on 18 September 2017
42. Sentinel lymph node biopsy plus wide local excision vs. wide location excision alone for primary cutaneous melanoma: a systematic review and meta‐analysis: (Publication); Background: Sentinel lymph node biopsy and wide local excision of the primary melanoma (SLNB) is now a standard staging procedure for patients with melanomas 1 mm or more in thickness, but its therapeutic ...; Created on 18 September 2017
43. A multicomponent index for a quick diagnosis of peritonitis in peritoneal dialysis patients: (Publication); Introduction and aims: Peritoneal infection (PI) is very frecuent and negatively impacts on survival of peritoneal dialysis technique. Currently, the gold standard for the diagnosis of ""typical"" bacterial ...; Created on 18 September 2017
44. The adverse prognostic effect of tumor budding on the evolution of cutaneous head and neck squamous cell carcinoma.: (Publication); Background: Tumor budding is a readily detectable histopathologic feature that has been recognized as an adverse prognostic factor in several human cancers. Objective: We sought to assess the correlation ...; Created on 18 September 2017
45. Tumor programmed cell death ligand 1 expression correlates with nodal metastasis in patients with cutaneous squamous cell carcinoma of the head and neck.: (Publication); Background: Binding of tumor-expressed programmed cell death ligand 1 (PD-L1) to the programmed cell death 1 (PD-1) surface receptor blocks T-cell activation thereby leading to immune evasion. Tumor PD-L1 ...; Created on 18 September 2017
46. A study of risks of Bayes estimators in the generalized half-logistic distribution for progressively type-II censored samples: (Publication); The problem of estimation of the shape parameter in a generalized half-logistic distribution for progressively type-II censored samples is of interest in reliability and survival analysis. In this paper, ...; Created on 18 September 2017
47. Flat foot in a random population and its impact on quality of life and functionality: (Publication); Introduction: Flat foot is a common deformity in adults. It is characterized by medial rotation and plantar flexion of the talus, eversion of the calcaneus, collapsed medial arch and abduction of the forefoot. Aim: ...; Created on 18 September 2017
48. Incidence of cardiovascular events and associated risk factors in kidney transplant patients: a competing risks survival analysis: (Publication); Background: The high prevalence of cardiovascular risk factors among the renal transplant population accounts for increased mortality. The aim of this study is to determine the incidence of cardiovascular ...; Created on 18 September 2017
49. Non-parametric ROC summary statistics: (Publication); Receiver operating characteristic (ROC) curves are useful statistical tools for medi- cal diagnostic testing. It has been proved its capability to assess diagnostic marker’s ability to distinguish between ...; Created on 08 September 2017
50. condSURV: An R Package for the Estimation of the Conditional Survival Function for Ordered Multivariate Failure Time Data: (Publication); One major goal in clinical applications of time-to-event data is the estimation of survival with censored data. The usual nonparametric estimator of the survival function is the time-honored Kaplan-Meier ...; Created on 22 May 2018