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1. Assessment of assumptions of statistical analysis methods in randomised clinical trials: the what and how: (Publication); When analysing and presenting results ofrandomised clinical trials, trialists rarely report if or how underlying statisticalassumptions were validated. To avoid data-driven biased trial results, it should ...; Created on 29 January 2020
2. Multiscale supervised classification of point clouds with urban and forest applications: (Publication); We analyze the utility of multiscale supervised classification algorithms for object detection and extraction from laser scanning or photogrammetric point clouds. Only the geometric information (the point ...; Created on 22 November 2019
3. The role of the p-value in the multitesting problem: (Publication); Modern science frequently involves the analysis of large amount of quantitative information and the simultaneous testing of thousands or even hundreds of thousands null hypotheses. In this context, sometimes, ...; Created on 22 November 2019
4. Structural, Dermal and Ungual Characteristics of the Foot in Patients with Type II Diabetes: (Publication); Background and Objectives: Diabetes is a chronic and metabolic disease, considered as an important public health problem. The objective of this study was to determine the prevalence of podiatric pathology ...; Created on 20 November 2019
5. Methylation Assessment for the Prediction of Malignancy in Mediastinal Adenopathies Obtained by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Patients with Lung Cancer: (Publication); The evaluation of mediastinal lymph nodes is critical for the correct staging of patients with lung cancer (LC). Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally ...; Created on 26 September 2019
6. Effects of Family History on Relative and Absolute Risks for Colorectal Cancer: a Systematic Review and Meta-Analysis: (Publication); BACKGROUND & AIMS: Guidelines recommend individuals with familial colorectal cancer (FCC) to undergo colonoscopy surveillance instead of average-risk screening. However, these recommendations vary widely. ...; Created on 26 September 2019
7. Addition of a 161-SNP polygenic risk score to family history-based risk prediction: Impact on clinical management in non- BRCA1/2 breast cancer families: (Publication); Background The currently known breast cancer-associated single nucleotide polymorphisms (SNPs) are presently not used to guide clinical management. We explored whether a genetic test that incorporates ...; Created on 26 September 2019
8. The apparent genetic anticipation in PMS2-associated lynch syndrome families is explained by birth-cohort effect: (Publication); Background: PMS2-associated Lynch syndrome is characterized by a relatively low colorectal cancer penetrance compared with other Lynch syndromes. However, age at colorectal cancer diagnosis varies widely, ...; Created on 26 September 2019
9. Adjusting for bias introduced by instrumental variable estimation in the Cox proportional hazards model: (Publication); Instrumental variable (IV) methods are widely used for estimating average treatment effects in the presence of unmeasured confounders. However, the capability of existing IV procedures, and most notably ...; Created on 25 September 2019
10. Dimension reduction estimation for central mean subspace with missing multivariate response: (Publication); Multivariate response data often arise in practice and they are frequently subject to missingness. Under this circumstance, the standard sufficient dimension reduction (SDR) methods cannot be used directly. ...; Created on 25 September 2019
11. Relationship between damage and mortality in juvenile-onset systemic lupus erythematosus: Cluster analyses in a large cohort from the Spanish Society of Rheumatology Lupus Registry (RELESSER): (Publication); ... Clinics Damage Index. Using cluster analysis, groups of patients with similar patterns of damage manifestation were identified and compared. Results: Mean age (years)± S.D. at diagnosis was 14.2 ± 2.89; ...; Created on 24 September 2019
12. Treatment with tenofovir alafenamide fumarate worsens the lipid profile of HIV-infected patients versus treatment with tenofovir disoproxil fumarate, each coformulated with elvitegravir, cobicistat, and ...: (Publication); Two elvitegravir/cobicistat-based therapies combined with emtricitabine/tenofovir disoproxil fumarate (EVG/c/FTC/TDF) or emtricitabine/tenofovir alafenamide fumarate (EVG/c/FTC/TAF) are currently available ...; Created on 24 September 2019
13. Erectile dysfunction in patients with arterial hypertension. Cardiovascular risk and impact on their quality of life: (Publication); Objectives: Estimate the frequency of erectile dysfunction in patients with essential hypertension and associated variables, degree of control, cardiovascular risk and the impact on quality of life. Material ...; Created on 24 September 2019
14. Late HIV Diagnosis but Earlier Antiretroviral Treatment Initiation in Northwest Spain: Impact of Current Treatment Guidelines: (Publication); Background: Current HIV treatment guidelines recommend antiretroviral treatment (ART) initiation for all HIV-infected individuals regardless of CD4 count. This study evaluates the immunological and virological ...; Created on 24 September 2019
15. Prevalence of knee osteoarthritis in a random population sample in people aged 40 and over: (Publication); Introduction: Osteoarthritis is the osteoarticular disease with the highest prevalence worldwide. In industrialized countries, 80% of the population > 65 years suffers from it. Objectives: To determine ...; Created on 24 September 2019
16. Incidence rate and clinicopathological features of 62 atypical fibroxanthomas in a North-Western Spanish population: (Publication); Background/Objectives: Atypical fibroxanthoma (AFX) is a mesenchymal neoplasm of unknown incidence. It has been determined that AFX is a tumour with low aggressiveness as long as it is properly diagnosed. ...; Created on 24 September 2019
17. Discovery of an autoantibody signature for the early diagnosis of knee osteoarthritis: Data from the Osteoarthritis Initiative: (Publication); Objective: To find autoantibodies (AAbs) in serum that could be useful to predict incidence of radiographic knee osteoarthritis (KOA). Design: A Nucleic-acid Programmable Protein Arrays (NAPPA) platform ...; Created on 24 September 2019
18. Cultural differences, language attitudes and tourist satisfaction: a study in the Barcelona hotel sector: (Publication); In most service activities, customer satisfaction depends largely on the direct interaction with service providers. In the case of tourism, this interaction often occurs between people from different countries ...; Created on 24 September 2019
19. A two-sample test for the equality of univariate marginal distributions for high-dimensional data: (Publication); A recurring theme in modern statistics is dealing with high-dimensional data whose main feature is a large number, p, of variables but a small sample size. In this context our aim is to address the problem ...; Created on 23 September 2019
20. A method for determining groups in multiple survival curves: (Publication); Survival analysis includes a wide variety of methods for analyzing time‐to‐event data. One basic but important goal in survival analysis is the comparison of survival curves between groups. Several nonparametric ...; Created on 23 August 2019
21. Systematic review with meta‐analysis: risk factors for recurrent primary sclerosing cholangitis after liver transplantation: (Publication); Background After liver transplantation primary sclerosing cholangitis (PSC), the condition returns in the transplanted liver in a subset of patients (recurrent primary sclerosing cholangitis, rPSC). Aim To ...; Created on 23 August 2019
22. The apparent genetic anticipation effect in PMS2-associated Lynch syndrome families is explained by birth-cohort effect: (Publication); Background: PMS2-associated Lynch syndrome is characterized by a relatively low colorectal cancer penetrance compared with other Lynch syndromes. However, age at colorectal cancer diagnosis varies widely, ...; Created on 23 August 2019
23. A comparative analysis of long-term mortality after carotid endarterectomy and carotid stenting: (Publication); Background The value of carotid intervention is predicated on long-term survival for patients to derive a stroke prevention benefit. Randomized trials report no significant difference in survival after ...; Created on 22 August 2019
24. Adverse Events After Atherectomy: Analyzing Long‐Term Outcomes of Endovascular Lower Extremity Revascularization Techniques: (Publication); Background The long-term effectiveness of atherectomy treatment for peripheral arterial disease is unknown. We studied 5-year clinical outcomes by endovascular treatment type among patients with peripheral ...; Created on 22 August 2019
25. A hybrid ARIMA–SVM model for the study of the remaining useful life of aircraft engines: (Publication); In this research, an algorithm is presented for predicting the remaining useful life (RUL) of aircraft engines from a set of predictor variables measured by several sensors located in the engine. RUL prediction ...; Created on 10 October 2018
26. Serum phosphate optimal timing and range associated with patients survival in haemodialysis: the COSMOS study: (Publication); Background Serum phosphate is a key parameter in the management of chronic kidney disease-mineral and bone disorder (CKD-MBD). The timing of phosphate measurement is not standardized in the current guidelines. ...; Created on 10 October 2018
27. Bootstrap-based testing approaches for the assessment of the diagnostic accuracy of biomarkers subject to a limit of detection: (Publication); Assessment of the diagnostic accuracy of biomarkers through receiver operating characteristic curve analysis frequently involves a limit of detection imposed by the laboratory analytical system precision. ...; Created on 09 October 2018
28. Spatial heterogeneity in Spain for senior travel behavior: (Publication); Travel patterns are becoming more differentiated, influenced by new variables resulting from changes in lifestyle. The relevance of the senior segment for this industry, with the continuous aging population ...; Created on 08 October 2018
29. Diagnostic accuracy of STOP-Bang questionnaire on moderate sleep apnoea in primary care: (Publication); OBJECTIVE: We aimed to compare the diagnostic utility of the STOP-Bang questionnaire for moderate apnoea against the gold standard (type I polysomnography) in a primary care setting. METHOD: Study of ...; Created on 02 October 2018
30. Parametric estimates for the receiver operating characteristic curve generalization for non-monotone relationships: (Publication); Diagnostic procedures are based on establishing certain conditions and then checking if those conditions are satisfied by a given individual. When the diagnostic procedure is based on a continuous marker, ...; Created on 22 May 2018
31. Bayesian nonparametric inference for the covariate-adjusted ROC curve: (Publication); Accurate diagnosis of disease is of fundamental importance in clinical practice and medical research. Before a medical diagnostic test is routinely used in practice, its ability to distinguish between ...; Created on 10 October 2018
32. nsROC: An R package for non-standard ROC curve analysis: (Publication); The receiver operating characteristic (ROC) curve is a graphical method which has become standard in the analysis of diagnostic markers, that is, in the study of the classiﬁcation ability of a numerical ...; Created on 10 October 2018
33. THU0359 Relationship between damage clustering and mortality in juvenile systemic lupus erythematosus: cluster analyses in a large cohort from the spanish society of rheumatology lupus registry: (Publication); ... Lupus International Collaborating Clinics Damage Index. Using cluster analysis, groups of patients with similar patterns of damage manifestation were identified and compared. Results: Mean age (years) ...; Created on 08 October 2018
34. Erectile dysfunction in patients with arterial hypertension. Cardiovascular risk and impact on their quality of life: (Publication); OBJECTIVES: Estimate the frequency of erectile dysfunction in patients with essential hypertension and associated variables, degree of control, cardiovascular risk and the impact on quality of life. MATERIAL ...; Created on 08 October 2018
35. Predictive factors of satisfaction and quality of life after immediate breast reconstruction using the BREAST-Q: (Publication); Aims and objectives: To analyse quality of life and satisfaction after immediate breast reconstruction due to cancer and its determining factors. Background: Studying breast reconstruction is important ...; Created on 08 October 2018
36. Comments on "One-tailed asymptotic inferences for the difference of proportions: analysis of 97 methods of inference" by Alvarez Hernandez M, Martin Andres A and Herranz Tejedor I. (2018): (Publication); Two-tailed asymptotic inferences for the difference d = p2 − p1 with independent proportions have been widely studied in the literature. Nevertheless, the case of one tail has received less attention, ...; Created on 03 October 2018
37. Penalized empirical likelihood for quantile regression with missing covariates and auxiliary information: (Publication); Based on the inverse probability weight method, we, in this article, construct the empirical likelihood (EL) and penalized empirical likelihood (PEL) ratios of the parameter in the linear quantile regression ...; Created on 01 October 2018
38. Estimation of monotone bivariate quantile residual life: (Publication); The bivariate quantile residual life function can play an important role in statistical reliability and survival analysis. In many situations assuming a decreasing form for it is recommended. Here, we ...; Created on 28 September 2018
39. A new approach to epigenome-wide discovery of non-invasive methylation biomarkers for colorectal cancer screening in circulating cell-free DNA using pooled samples o: (Publication); Background: Colorectal cancer is the fourth cause of cancer-related deaths worldwide, though detection at early stages associates with good prognosis. Thus, there is a clear demand for novel non-invasive ...; Created on 22 May 2018
40. Survival analysis with delayed entry in selected families with application to human longevity: (Publication); In the field of aging research, family-based sampling study designs are commonly used to study the lifespans of long-lived family members. However, the specific sampling procedure should be carefully taken ...; Created on 22 May 2018
41. Improving stability of prediction models based on correlated omics data by using network approaches: (Publication); Building prediction models based on complex omics datasets such as transcriptomics, proteomics, metabolomics remains a challenge in bioinformatics and biostatistics. Regularized regression techniques are ...; Created on 22 May 2018
42. Performance of BRCA1/2 mutation prediction models in male breast cancer patients: (Publication); To establish whether existing mutation prediction models can identify which male breast cancer (MBC) patients should be offered BRCA1 and BRCA2 diagnostic DNA screening, we compared the performance of ...; Created on 22 May 2018
43. Bootstrap-based procedures for inference in nonparametric receiver-operating characteristic curve regression analysis: (Publication); Prior to using a diagnostic test in a routine clinical setting, the rigorous evaluation of its diagnostic accuracy is essential. The receiver-operating characteristic curve is the measure of accuracy most ...; Created on 22 May 2018
44. Large-scale external validation and comparison of prognostic models: an application to chronic obstructive pulmonary disease: (Publication); Background: External validations and comparisons of prognostic models or scores are a prerequisite for their use in routine clinical care but are lacking in most medical fields including chronic obstructive ...; Created on 22 May 2018
45. Geographically Weighted Principal Components Analysis to assess diffuse pollution sources of soil heavy metal: Application to rough mountain areas in Northwest Spain.: (Publication); Heavy metal pollution can result in the degradation of the soil, air and water bodies' quality affecting the health of all living organism. We analyze the spatial distribution of the concentrations of ...; Created on 24 January 2018
46. Quantile regression for partially linear varying-coefficient model with censoring indicators missing at random: (Publication); In this paper, we focus on the partially linear varying-coefficient quantile regression model when the data are right censored and the censoring indicator is missing at random. Based on the calibration ...; Created on 24 January 2018
47. Correcting for spatial heterogeneity in plant breeding experiments with P-splines: (Publication); An important aim of the analysis of agricultural field experiments is to obtain good predictions for genotypic performance, by correcting for spatial effects. In practice these corrections turn out to ...; Created on 24 January 2018
48. On coalition formation in a non-convex multi-agent inventory problem: (Publication); A multi-agent inventory problem is a situation in which several agents face individual inventory problems and can coordinate their orders to reduce costs. This paper analyses a multi-agent inventory problem ...; Created on 18 September 2017
49. On the Combination of Omics Data for Prediction of Binary Outcomes: (Publication); Enrichment of predictive models with new biomolecular markers is an important task in high-dimensional omic applications. Increasingly, clinical studies include several sets of such omics markers available ...; Created on 10 October 2018
50. Adjusting for bias introduced by instrumental variable estimation in the Cox proportional hazards model: (Publication); Instrumental variable (IV) methods are widely used for estimating average treatment effects in the presence of unmeasured confounders. However, the capability of existing IV procedures, and most notably ...; Created on 10 October 2018