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1. Multiscale supervised classification of point clouds with urban and forest applications: (Publication); We analyze the utility of multiscale supervised classification algorithms for object detection and extraction from laser scanning or photogrammetric point clouds. Only the geometric information (the point ...; Created on 22 November 2019
2. Traditional Processed Meat Products Re-designed Towards Inulin-rich Functional Foods Reduce Polyps in Two Colorectal Cancer Animal Models: (Publication); Inulin-rich foods exert a prebiotic effect, as this polysaccharide is able to enhance beneficial colon microbiota populations, giving rise to the in situ production of short-chain fatty acids (SCFAs) such ...; Created on 22 November 2019
3. Methylation Assessment for the Prediction of Malignancy in Mediastinal Adenopathies Obtained by Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Patients with Lung Cancer: (Publication); The evaluation of mediastinal lymph nodes is critical for the correct staging of patients with lung cancer (LC). Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally ...; Created on 26 September 2019
4. On the estimation of variance parameters in non-standard generalised linear mixed models: application to penalised smoothing: (Publication); We present a novel method for the estimation of variance parameters in generalised linear mixed models. The method has its roots in Harville (J Am Stat Assoc 72(358):320–338, 1977)’s work, but it is able ...; Created on 25 September 2019
5. On the optimism correction of the area under the receiver operating characteristic curve in logistic prediction models: (Publication); When the same data are used to fit a model and estimate its predictive performance, this estimate may be optimistic, and its correction is required. The aim of this work is to compare the behaviour of ...; Created on 25 September 2019
6. Goodness-of-fit tests for quantile regression with missing responses: (Publication); Goodness–of–fit tests for quantile regression models, in the presence of missing observations in the response variable, are introduced and analyzed in this paper. The different proposals are based on the ...; Created on 19 September 2019
7. Predicting pollution incidents through semiparametric quantile regression models: (Publication); In this paper we present a method to forecast pollution episodes using measurements of the pollutant concentration along time. Specifically, we use a backfitting algorithm with local polynomial kernel ...; Created on 18 September 2019
8. Goodness-of-fit tests for parametric specifications of conditionally heteroscedastic models: (Publication); We consider a goodness-of-fit test for certain parametrizations of conditionally heteroscedastic time series with unobserved components. Our test is quite general in that it can be employed to validate ...; Created on 17 September 2019
9. Estimation in the progressive illness-death model: a non-exhaustive review: (Publication); Multistate models can be successfully used for describing complex event history data, for example, describing stages in the disease progression of a patient. The so‐called “illness‐death” model plays a ...; Created on 23 August 2019
10. Testing critical points of nonparametric regression curves: application to the management of stalked barnacles: (Publication); Several aquatic living resources are overexploited. An example of this is a barnacle fishery, which is a commercial species that commands high prices in the market. We feel that not enough is known about ...; Created on 23 August 2019
11. Circulating microRNAs in suspected stable coronary artery disease: A coronary computed tomography angiography study: (Publication); Objectives To explore the diagnostic performance of circulating microRNAs (miRNAs) as biomarkers in patients with suspected stable coronary artery disease (CAD). Methods Plasma samples were collected ...; Created on 22 August 2019
12. Plasma microRNA Profiling Reveals Novel Biomarkers of Epicardial Adipose Tissue: A Multidetector Computed Tomography Study: (Publication); Epicardial adipose tissue (EAT) constitutes a novel parameter for cardiometabolic risk assessment and a target for therapy. Here, we evaluated for the first time the plasma microRNA (miRNA) profile as ...; Created on 22 August 2019
13. An instrumental variable procedure for estimating Cox models with non‐proportional hazards in the presence of unmeasured confounding: (Publication); Two‐stage instrumental variable methods are commonly used for estimating average causal effects in the presence of an unmeasured confounder. In the context of the proportional hazard Cox regression models, ...; Created on 22 August 2019
14. External Validation and Recalculation of the CODEX Index in COPD Patients. A 3CIAplus Cohort Study: (Publication); The CODEX index was developed and validated in patients hospitalized for COPD exacerbation to predict the risk of death and readmission within one year after discharge. Our study aimed to validate the ...; Created on 22 August 2019
15. Lectin-like transcript 1 (LLT1) expression is associated with nodal metastasis in patients with head and neck cutaneous squamous cell carcinoma: (Publication); The interaction of lectin-like transcript 1 (LLT1) with CD161 inhibits Natural Killer cell activation. Overexpression of LLT1 contributes to the immunosuppressive properties of tumor cells. However, there ...; Created on 22 August 2019
16. Serum phosphate optimal timing and range associated with patients survival in haemodialysis: the COSMOS study: (Publication); Background Serum phosphate is a key parameter in the management of chronic kidney disease-mineral and bone disorder (CKD-MBD). The timing of phosphate measurement is not standardized in the current guidelines. ...; Created on 10 October 2018
17. Characterization of multinormality and corresponding tests of fit, including for GARCH models: (Publication); We provide novel characterizations of multivariate normality that incorporate both the characteristic function and the moment generating function, and we employ these results to construct a class of affine ...; Created on 09 October 2018
18. A two-sample test for the error distribution in nonparametric regression based on the characteristic function: (Publication); A test for the equality of error distributions in two nonparametric regression models is proposed. The test statistic is based on comparing the empirical characteristic functions of the residuals calculated ...; Created on 09 October 2018
19. Body mass index transitions during childhood: a multiple-state model approach: (Publication); Introduction Childhood obesity is of major public health concern with significant health, social and economic impacts, having even potential to reverse the increase in longevity that has been observed. ...; Created on 06 March 2019
20. Percentile curves and reference values for 2000-m rowing ergometer performance time in international rowers aged 14-70 years: (Publication); The aim of this study was to provide percentile curves and reference values for the performance in 2000-m maximal effort on rowing ergometer. A cross-sectional study was carried out with a non-probabilistic ...; Created on 11 October 2018
21. Bayesian nonparametric inference for the covariate-adjusted ROC curve: (Publication); Accurate diagnosis of disease is of fundamental importance in clinical practice and medical research. Before a medical diagnostic test is routinely used in practice, its ability to distinguish between ...; Created on 10 October 2018
22. Sequential double cross-validation for assessment of added predictive ability in high-dimensional OMIC applications: (Publication); Enriching existing predictive models with new biomolecular markers is an important task in the new multi-omic era. Clinical studies increasingly include new sets of omic measurements which may prove their ...; Created on 03 October 2018
23. On the estimation of variance parameters in non-standard generalised linear mixed models: application to penalised smoothing: (Publication); We present a novel method for the estimation of variance parameters in generalised linear mixed models. The method has its roots in Harville (J Am Stat Assoc 72(358):320–338, 1977)’s work, but it is able ...; Created on 02 October 2018
24. SIMPLIFY ITS An Intelligent Tutoring System based on Cognitive Diagnosis Models and spaced learning: (Publication); In this paper we introduce Simplify ITS, a novel approach to an adaptive and Intelligent Tutoring System (ITS) aimed to support teachers in enhancing the student know ledge and skills. Unlike other approaches, ...; Created on 01 October 2018
25. Penalized profile least squares-based statistical inference for varying coefficient partially linear errors-in-variables models: (Publication); The purpose of this paper is two fold. First, we investigate estimation for varying coefficient partially linear models in which covariates in the nonparametric part are measured with errors. As there ...; Created on 01 October 2018
26. Asymptotic distribution-free tests for semiparametric regressions with dependent data: (Publication); This article proposes a new general methodology for constructing nonparametric and semiparametric Asymptotically Distribution-Free (ADF) tests for semiparametric hypotheses in regression models for possibly ...; Created on 22 May 2018
27. Survival analysis with delayed entry in selected families with application to human longevity: (Publication); In the field of aging research, family-based sampling study designs are commonly used to study the lifespans of long-lived family members. However, the specific sampling procedure should be carefully taken ...; Created on 22 May 2018
28. Improving stability of prediction models based on correlated omics data by using network approaches: (Publication); Building prediction models based on complex omics datasets such as transcriptomics, proteomics, metabolomics remains a challenge in bioinformatics and biostatistics. Regularized regression techniques are ...; Created on 22 May 2018
29. Performance of BRCA1/2 mutation prediction models in male breast cancer patients: (Publication); To establish whether existing mutation prediction models can identify which male breast cancer (MBC) patients should be offered BRCA1 and BRCA2 diagnostic DNA screening, we compared the performance of ...; Created on 22 May 2018
30. Bootstrap-based procedures for inference in nonparametric receiver-operating characteristic curve regression analysis: (Publication); Prior to using a diagnostic test in a routine clinical setting, the rigorous evaluation of its diagnostic accuracy is essential. The receiver-operating characteristic curve is the measure of accuracy most ...; Created on 22 May 2018
31. Large-scale external validation and comparison of prognostic models: an application to chronic obstructive pulmonary disease: (Publication); Background: External validations and comparisons of prognostic models or scores are a prerequisite for their use in routine clinical care but are lacking in most medical fields including chronic obstructive ...; Created on 22 May 2018
32. Computationally Efficient Goodness-of-Fit Tests for the Error Distribution in Nonparametric Regression: (Publication); Several procedures have been proposed for testing goodness-of-fit to the error distribution in nonparametric regression models. The null distribution of the associated test statistics is usually approximated ...; Created on 14 May 2018
33. Inverse Probability Weighted Cox Regression for Doubly Truncated Data: (Publication); Doubly truncated data arise when event times are observed only if they fall within subject-specific, possibly random, intervals. While non-parametric methods for survivor function estimation using doubly ...; Created on 20 February 2018
34. Determining optimum wavelengths for leaf water content estimation from reflectance: A distance correlation approach: (Publication); This paper proposes a method to estimate leaf water content from reflectance in four commercial vineyard varieties by estimating the local maxima of a distance correlation function. First, it applies four ...; Created on 24 January 2018
35. On the Combination of Omics Data for Prediction of Binary Outcomes: (Publication); Enrichment of predictive models with new biomolecular markers is an important task in high-dimensional omic applications. Increasingly, clinical studies include several sets of such omics markers available ...; Created on 10 October 2018
36. A weighted bootstrap approximation for comparing the error distributions in nonparametric regression: (Publication); Several procedures have been proposed for testing the equality of error distributions in two or more nonparametric regression models. Here we deal with methods based on comparing estimators of the cumulative ...; Created on 09 October 2018
37. A new approach to categorising continuous variables in prediction models: Proposal and validation: (Publication); When developing prediction models for application in clinical practice, health practitioners usually categorise clinical variables that are continuous in nature. Although categorisation is not regarded ...; Created on 22 May 2018
38. Jackknife empirical likelihood of error variance in partially linear varying-coefficient errors-in-variables models: (Publication); For the partially linear varying-coefficient model when the parametric covariates are measured with additive errors, the estimator of the error variance is defined based on residuals of the model. At the ...; Created on 22 May 2018
39. Empirical characteristic function tests for GARCH innovation distribution using multipliers: (Publication); Goodness-of-fit tests for the innovation distribution in GARCH models based on measuring deviations between the empirical characteristic function of the residuals and the characteristic function under ...; Created on 23 January 2018
40. Comparing some production functions for inpatient health services in selected public hospitals in Spain: (Publication); To investigate the adequacy of the widely used Cobb-Douglas and transcendental logarithmic (translog) models of the production functions of hospital inpatient services, the authors fitted these and additive ...; Created on 18 September 2017
41. Modelling spatial trends in sorghum breeding field trials using a two-dimensional P-spline mixed model: (Publication); Adjustment for spatial trends in plant breeding field trials is essential for efficient evaluation and selection of genotypes. Current mixed model methods of spatial analysis are based on a multi-step ...; Created on 18 September 2017
42. npregfast: an R package for nonparametric estimation and inference in life sciences: (Publication); We present the R npregfast package via some applications involved with the study of living organisms. The package implements nonparametric estimation procedures in regression models with or without factor-by-curve ...; Created on 18 September 2017
43. Cisplatin resistance in cell models: evaluation of metallomic and biological predictive biomarkers to address early therapy failure: (Publication); Cisplatin, one of the most extensively used metallodrugs in cancer treatment, presents the important drawback of patient resistance. This resistance is the consequence of different processes including ...; Created on 18 September 2017
44. Fully non-parametric receiver operating characteristic curve estimation for random-effects meta-analysis: (Publication); Meta-analyses, broadly defined as the quantitative review and synthesis of the results of related but independent comparable studies, allow to know the state of the art of one considered topic. Since the ...; Created on 18 September 2017
45. Tumor programmed cell death ligand 1 expression correlates with nodal metastasis in patients with cutaneous squamous cell carcinoma of the head and neck.: (Publication); Background: Binding of tumor-expressed programmed cell death ligand 1 (PD-L1) to the programmed cell death 1 (PD-1) surface receptor blocks T-cell activation thereby leading to immune evasion. Tumor PD-L1 ...; Created on 18 September 2017
46. Pillar[5]arene-based supramolecular plasmonic thin films for label-free, quantitative and multiplex SERS detection: (Publication); Novel plasmonic thin films based on electrostatic layer-by-layer (LbL) deposition of citrate-stabilized Au nanoparticles (NPs) and ammonium pillar[5]arene (AP[5]A) have been developed. The supramolecular-induced ...; Created on 18 September 2017
47. Incidence of cardiovascular events and associated risk factors in kidney transplant patients: a competing risks survival analysis: (Publication); Background: The high prevalence of cardiovascular risk factors among the renal transplant population accounts for increased mortality. The aim of this study is to determine the incidence of cardiovascular ...; Created on 18 September 2017
48. Tests for conditional ellipticity in multivariate GARCH models: (Publication); Tests are proposed for the assumption that the conditional distribution of a multivariate GARCH process is elliptic. These tests are of Kolmogorov–Smirnov and Cramér–von Mises-type and make use of the ...; Created on 18 January 2017
49. Survival analysis with delayed entry in selected families with application to human longevity: (Publication); In the field of aging research, family-based sampling study designs are commonly used to study the lifespans of long-lived family members. However, the specific sampling procedure should be carefully taken ...; Created on 18 September 2017
50. FWDselect: An R Package for Variable Selection in Regression Models: (Publication); In multiple regression models, when there are a large number (p) of explanatory variables which may or may not be relevant for predicting the response, it is useful to be able to reduce the model. To this ...; Created on 08 September 2017