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1. Assessment of assumptions of statistical analysis methods in randomised clinical trials: the what and how: (Publication); When analysing and presenting results ofrandomised clinical trials, trialists rarely report if or how underlying statisticalassumptions were validated. To avoid data-driven biased trial results, it should ...; Created on 29 January 2020
2. Nonparametric estimation of the cumulative incidences of competing risks under double truncation: (Publication); Registry data typically report incident cases within a certain calendar time interval. Such interval sampling induces double truncation on the incidence times, which may result in an observational bias. ...; Created on 21 January 2020
3. Testing for superiority between two variance functions: (Publication); This paper focuses on the problem of testing the null hypothesis that the variance functions of two populations are equal versus one-sided alternatives under a general nonparametric heteroscedastic regression ...; Created on 16 September 2019
4. Traditional Processed Meat Products Re-designed Towards Inulin-rich Functional Foods Reduce Polyps in Two Colorectal Cancer Animal Models: (Publication); Inulin-rich foods exert a prebiotic effect, as this polysaccharide is able to enhance beneficial colon microbiota populations, giving rise to the in situ production of short-chain fatty acids (SCFAs) such ...; Created on 22 November 2019
5. The role of the p-value in the multitesting problem: (Publication); Modern science frequently involves the analysis of large amount of quantitative information and the simultaneous testing of thousands or even hundreds of thousands null hypotheses. In this context, sometimes, ...; Created on 22 November 2019
6. Structural, Dermal and Ungual Characteristics of the Foot in Patients with Type II Diabetes: (Publication); Background and Objectives: Diabetes is a chronic and metabolic disease, considered as an important public health problem. The objective of this study was to determine the prevalence of podiatric pathology ...; Created on 20 November 2019
7. Addition of a 161-SNP polygenic risk score to family history-based risk prediction: Impact on clinical management in non- BRCA1/2 breast cancer families: (Publication); Background The currently known breast cancer-associated single nucleotide polymorphisms (SNPs) are presently not used to guide clinical management. We explored whether a genetic test that incorporates ...; Created on 26 September 2019
8. The apparent genetic anticipation in PMS2-associated lynch syndrome families is explained by birth-cohort effect: (Publication); Background: PMS2-associated Lynch syndrome is characterized by a relatively low colorectal cancer penetrance compared with other Lynch syndromes. However, age at colorectal cancer diagnosis varies widely, ...; Created on 26 September 2019
9. On the optimism correction of the area under the receiver operating characteristic curve in logistic prediction models: (Publication); When the same data are used to fit a model and estimate its predictive performance, this estimate may be optimistic, and its correction is required. The aim of this work is to compare the behaviour of ...; Created on 25 September 2019
10. Time trends in prevalence and incidence rates of childhood overweight and obesity in Portugal: Generation XXI birth cohort: (Publication); Childhood obesity estimates are steadily increasing worldwide. There is strong evidence that overweight children before puberty maintain this nutritional status for life. This study aimed to estimate the ...; Created on 25 September 2019
11. Gestational Weight Gain and Offspring Bone Mass: Different Associations in Healthy Weight Versus Overweight Women: (Publication); Weight management strategies during pregnancy reduce child cardiometabolic risk. However, because maternal weight has an overall positive correlation with offspring bone mass, pregnancy weight management ...; Created on 25 September 2019
12. Time trends in prevalence and incidence rates of childhood overweight and obesity in Portugal: Generation XXI birth cohort: (Publication); Childhood obesity estimates are steadily increasing worldwide. There is strong evidence that overweight children before puberty maintain this nutritional status for life. This study aimed to estimate the ...; Created on 25 September 2019
13. Adjusting for bias introduced by instrumental variable estimation in the Cox proportional hazards model: (Publication); Instrumental variable (IV) methods are widely used for estimating average treatment effects in the presence of unmeasured confounders. However, the capability of existing IV procedures, and most notably ...; Created on 25 September 2019
14. CLT for integrated square error of density estimators with censoring indicators missing at random: (Publication); A popular stochastic measure of the distance between the density of the lifetimes and its estimator is the integrated square error (ISE) and Hellinger distance (HD). In this paper, we focus on the right-censored ...; Created on 25 September 2019
15. Asymptotic normality of conditional density estimation under truncated, censored and dependent data: (Publication); In this paper, we focus on the left-truncated and right-censored model, and construct the local linear and Nadaraya-Watson type estimators of the conditional density. Under suitable conditions, we establish ...; Created on 25 September 2019
16. Late HIV Diagnosis but Earlier Antiretroviral Treatment Initiation in Northwest Spain: Impact of Current Treatment Guidelines: (Publication); Background: Current HIV treatment guidelines recommend antiretroviral treatment (ART) initiation for all HIV-infected individuals regardless of CD4 count. This study evaluates the immunological and virological ...; Created on 24 September 2019
17. Post-stroke shoulder pain subtypes classifying criteria: towards a more specific assessment and improved physical therapeutic care: (Publication); Background: Post-stroke Shoulder Pain (PSSP) is a common stroke-related syndrome that prolongs hospitalization and diminishes quality of life. PSSP studies were unsuccessful in clarifying pathophysiological ...; Created on 24 September 2019
18. Prevalence of knee osteoarthritis in a random population sample in people aged 40 and over: (Publication); Introduction: Osteoarthritis is the osteoarticular disease with the highest prevalence worldwide. In industrialized countries, 80% of the population > 65 years suffers from it. Objectives: To determine ...; Created on 24 September 2019
19. A two-sample test for the equality of univariate marginal distributions for high-dimensional data: (Publication); A recurring theme in modern statistics is dealing with high-dimensional data whose main feature is a large number, p, of variables but a small sample size. In this context our aim is to address the problem ...; Created on 23 September 2019
20. Goodness-of-fit tests for quantile regression with missing responses: (Publication); Goodness–of–fit tests for quantile regression models, in the presence of missing observations in the response variable, are introduced and analyzed in this paper. The different proposals are based on the ...; Created on 19 September 2019
21. Predicting pollution incidents through semiparametric quantile regression models: (Publication); In this paper we present a method to forecast pollution episodes using measurements of the pollutant concentration along time. Specifically, we use a backfitting algorithm with local polynomial kernel ...; Created on 18 September 2019
22. Goodness-of-fit tests for parametric specifications of conditionally heteroscedastic models: (Publication); We consider a goodness-of-fit test for certain parametrizations of conditionally heteroscedastic time series with unobserved components. Our test is quite general in that it can be employed to validate ...; Created on 17 September 2019
23. On goodness-of-fit tests for the Bell distribution: (Publication); The one-parameter Bell family of distributions, introduced by Castellares et al. (Appl Math Model 56:172–185, 2018), is useful for modeling count data. This paper proposes and studies a goodness-of-fit ...; Created on 17 September 2019
24. Estimation in the progressive illness-death model: a non-exhaustive review: (Publication); Multistate models can be successfully used for describing complex event history data, for example, describing stages in the disease progression of a patient. The so‐called “illness‐death” model plays a ...; Created on 23 August 2019
25. A method for determining groups in multiple survival curves: (Publication); Survival analysis includes a wide variety of methods for analyzing time‐to‐event data. One basic but important goal in survival analysis is the comparison of survival curves between groups. Several nonparametric ...; Created on 23 August 2019
26. The apparent genetic anticipation effect in PMS2-associated Lynch syndrome families is explained by birth-cohort effect: (Publication); Background: PMS2-associated Lynch syndrome is characterized by a relatively low colorectal cancer penetrance compared with other Lynch syndromes. However, age at colorectal cancer diagnosis varies widely, ...; Created on 23 August 2019
27. Testing critical points of nonparametric regression curves: application to the management of stalked barnacles: (Publication); Several aquatic living resources are overexploited. An example of this is a barnacle fishery, which is a commercial species that commands high prices in the market. We feel that not enough is known about ...; Created on 23 August 2019
28. Improving the biomarker diagnostic capacity via functional transformations: (Publication); The use of the area under the receiver-operating characteristic, ROC, curve (AUC) as an index of diagnostic accuracy is overwhelming in fields such as biomedical science and machine learning. It seems ...; Created on 22 August 2019
29. An instrumental variable procedure for estimating Cox models with non‐proportional hazards in the presence of unmeasured confounding: (Publication); Two‐stage instrumental variable methods are commonly used for estimating average causal effects in the presence of an unmeasured confounder. In the context of the proportional hazard Cox regression models, ...; Created on 22 August 2019
30. External Validation and Recalculation of the CODEX Index in COPD Patients. A 3CIAplus Cohort Study: (Publication); The CODEX index was developed and validated in patients hospitalized for COPD exacerbation to predict the risk of death and readmission within one year after discharge. Our study aimed to validate the ...; Created on 22 August 2019
31. Goodness-of-fit tests for disorder detection in NGS experiments: (Publication); Next‐generation sequencing (NGS) experiments are often performed in biomedical research nowadays, leading to methodological challenges related to the high‐dimensional and complex nature of the recorded ...; Created on 06 August 2019
32. Hubert's multi‐rater kappa revisited: (Publication); There is a frequent need to measure the degree of agreement among R observers who independently classify n subjects within K nominal or ordinal categories. The most popular methods are usually kappa‐type ...; Created on 06 August 2019
33. Testing equality of a large number of densities under mixing conditions: (Publication); In certain settings, such as microarray data, the sampling information is formed by a large number of possibly dependent small data sets. In special applications, for example in order to perform clustering, ...; Created on 12 December 2018
34. Testing for the Poisson-Tweedie distribution: (Publication); In practice, count data exhibit over-dispersion, zero-inflation and even heavy tails. The Poisson–Tweedie distribution is a flexible parametric family able to accommodate these features. This paper proposes ...; Created on 09 October 2018
35. A model specification test for the variance function in nonparametric regression: (Publication); The problem of testing for the parametric form of the conditional variance is considered in a fully nonparametric regression model. A test statistic based on a weighted L2-distance between the empirical ...; Created on 09 October 2018
36. A new class of tests for multinormality with i.i.d. and garch data based on the empirical moment generating function: (Publication); We generalize a recent class of tests for univariate normality that are based on the empirical moment generating function to the multivariate setting, thus obtaining a class of affine invariant, consistent ...; Created on 09 October 2018
37. Characterization of multinormality and corresponding tests of fit, including for GARCH models: (Publication); We provide novel characterizations of multivariate normality that incorporate both the characteristic function and the moment generating function, and we employ these results to construct a class of affine ...; Created on 09 October 2018
38. Approximating the null distribution of a class of statistics for testing independence: (Publication); A class of tests for testing independence whose test statistic is an -norm of the difference between the joint empirical characteristic function and the product of the marginal empirical characteristic ...; Created on 09 October 2018
39. A two-sample test for the error distribution in nonparametric regression based on the characteristic function: (Publication); A test for the equality of error distributions in two nonparametric regression models is proposed. The test statistic is based on comparing the empirical characteristic functions of the residuals calculated ...; Created on 09 October 2018
40. Bootstrap-based testing approaches for the assessment of the diagnostic accuracy of biomarkers subject to a limit of detection: (Publication); Assessment of the diagnostic accuracy of biomarkers through receiver operating characteristic curve analysis frequently involves a limit of detection imposed by the laboratory analytical system precision. ...; Created on 09 October 2018
41. Diagnostic accuracy of STOP-Bang questionnaire on moderate sleep apnoea in primary care: (Publication); OBJECTIVE: We aimed to compare the diagnostic utility of the STOP-Bang questionnaire for moderate apnoea against the gold standard (type I polysomnography) in a primary care setting. METHOD: Study of ...; Created on 02 October 2018
42. Weighted estimation of conditional mean function with truncated, censored and dependent data: (Publication); By applying the empirical likelihood method, we construct a new weighted estimator of the conditional mean function for a left-truncated and right-censored model. Assuming that the observations form a ...; Created on 11 October 2018
43. Percentile curves and reference values for 2000-m rowing ergometer performance time in international rowers aged 14-70 years: (Publication); The aim of this study was to provide percentile curves and reference values for the performance in 2000-m maximal effort on rowing ergometer. A cross-sectional study was carried out with a non-probabilistic ...; Created on 11 October 2018
44. Game-Related Statistics in the Spanish Water Polo League: Differences between Seasons: (Publication); The aim of this study was to identify the differences between seasons in men´s water polo regular competition by analysing the changes of game-related statistics. The sample comprised 88 games from the ...; Created on 11 October 2018
45. Bayesian nonparametric inference for the covariate-adjusted ROC curve: (Publication); Accurate diagnosis of disease is of fundamental importance in clinical practice and medical research. Before a medical diagnostic test is routinely used in practice, its ability to distinguish between ...; Created on 10 October 2018
46. A Diagnostic Test Approach for Multitesting Problems: (Publication); In the last decades, multiple-testing problems have received much attention. Many different methods have been proposed in order to deal with this relevant issue. Most of them are focused on controlling ...; Created on 10 October 2018
47. Predictive factors of satisfaction and quality of life after immediate breast reconstruction using the BREAST-Q: (Publication); Aims and objectives: To analyse quality of life and satisfaction after immediate breast reconstruction due to cancer and its determining factors. Background: Studying breast reconstruction is important ...; Created on 08 October 2018
48. Comments on "One-tailed asymptotic inferences for the difference of proportions: analysis of 97 methods of inference" by Alvarez Hernandez M, Martin Andres A and Herranz Tejedor I. (2018): (Publication); Two-tailed asymptotic inferences for the difference d = p2 − p1 with independent proportions have been widely studied in the literature. Nevertheless, the case of one tail has received less attention, ...; Created on 03 October 2018
49. Inventorymodel: an R Package for Centralized Inventory Problems: (Publication); Inventory management of goods is an integral part of logistics systems; common to various economic sectors such as industry, agriculture and trade; and independent of production volume. In general, as ...; Created on 03 October 2018
50. Sequential double cross-validation for assessment of added predictive ability in high-dimensional OMIC applications: (Publication); Enriching existing predictive models with new biomolecular markers is an important task in the new multi-omic era. Clinical studies increasingly include new sets of omic measurements which may prove their ...; Created on 03 October 2018