Facultade de Fisioterapia

Cumulative/dynamic ROC curve estimation

Martínez Camblor, Pablo; Bayón, G.F.; Pérez Fernández, S.
Abstract:
Receiver operating-characteristic (ROC) curve is a popular graphical method frequently used in order to study the diagnostic capacity of continuous (bio)markers. When the considered outcome is a time-dependent variable, the direct generalization is known as cumulative/dynamic ROC curve. For a fixed point of time, t, one subject is allocated into the positive group if the event happens before t and into the negative group if the event is not happened at t. The presence of censored subject, which can not be directly assigned into a group, is the main handicap of this approach. The proposed cumulative/dynamic ROC curve estimator assigns a probability to belong to the negative (positive) group to the subjects censored previously to t. The performance of the resulting estimator is studied from Monte Carlo simulations. Some real-world applications are reported. Results suggest that the new estimators provide a good approximation to the real cumulative/dynamic ROC curve.
Year:
2016
Type of Publication:
Article
Journal:
Journal of Statistical Computation and Simulation
Volume:
86
Number:
17
Pages:
3582-3594
Month:
November
DOI:
https://doi.org/10.1080/00949655.2016.1175442
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