A multicomponent index for a quick diagnosis of peritonitis in peritoneal dialysis patients
Sánchez Alvarez, J.E.; M., Nuñez Moral; Martínez Camblor, Pablo; Méndez González, A.; Peláez Requejo, B.; Fernández Pérez, M.; González Díaz, I.; Rodríguez Suárez, C.
Introduction and aims: Peritoneal infection (PI) is very frecuent and negatively impacts on survival of peritoneal dialysis technique. Currently, the gold standard for the diagnosis of ""typical"" bacterial peritonitis is based on cloudy peritoneal effluent, leukocyte cell count greater than 100 leukocytes/microliter (L/μl) and more than 50% polymorphonuclear cells (PMN). To reduce complications derived from peritonitis, the rapid onset of treatment is recommended. This study develops the construction of a multi-component model (MUL+PA) for the diagnosis of PI, to be useful in clinical practice.
Methods: For our purpose, a cohort was used for the construction of the model, and later it was validated with another cohort, independent of the first one. The model construction cohort was generated by collecting information on effluent samples for the first 6 months of 2015.