Facultade de Fisioterapia

A Multistate Model for Analyzing Transitions Between Body Mass Index Categories During Childhood: The Generation XXI Birth Cohort Study

Moreira, Carla; Meira-Machado, Luis; Fonseca, Maria João; Santos, Ana Cristina
Abstract:
Prevalences of overweight and obesity in young children have risen dramatically in the last several decades in most developed countries. Childhood overweight and obesity are known to have immediate and long-term health consequences and are now recognized as important public health concerns. We used a Markov 4-state model with states defined by 4 body mass index (BMI; weight (kg)/height (m)2) categories (underweight (<−2 standard deviations (SDs) of BMI z score), normal weight (−2 ≤ SD ≤ 1), overweight (1 < SD ≤ 2), and obese (>2 SDs of BMI z score)) to study the rates of transition to higher or lower BMI categories among children aged 4–10 years. We also used this model to study the relationships between explanatory variables and their transition rates. The participants consisted of 4,887 children from the Generation XXI Birth Cohort Study (Porto, Portugal; 2005–2017) who underwent anthropometric evaluation at age 4 years and in at least 1 of the subsequent follow-up waves (ages 7 and 10 years). Children who were normal weight were more likely to move to higher BMI categories than to lower categories, whereas overweight children had similar rates of transition to the 2 adjacent categories. We evaluated the associations of maternal age and education, type of delivery, sex, and birth weight with childhood overweight and obesity, but we observed statistically significant results only for sex and maternal education with regard to the progressive transitions.
Year:
2019
Type of Publication:
Article
Keywords:
body mass index; body mass transitions; childhood obesity; Generation XXI; interval censoring; multistate models
Journal:
American Journal of Epidemiology
Volume:
188
Number:
2
Pages:
305–313
Month:
February
Note:
Q1 20/185 h-index 4.780 (JCR2018)
DOI:
https://doi.org/10.1093/aje/kwy232
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